Number of Protein Chains:8
- Classes: All alpha proteins
- Folds: Cyclin-like
- Superfamilies: Cyclin-like
- Families: Cyclin
- Protein Domains: Cyclin A
- Species: Human (Homo sapiens) [TaxId: 9606]
PDB Entries
PDB ID | OPM | Mutant | Chain Formula | Resolution | HETNAM | ||
---|---|---|---|---|---|---|---|
Amino Acid sequence | SCOPe Family Level | CATH Homology Level | |||||
1e9h | [AB] | [AB] | [AB] | 2.5 | INR:2___sq___,3-DIOXO-1,1___sq___,2___sq___,3-TETRAHYDRO-2,3___sq___-BIINDOLE-5___sq___-SULFONIC ACID TPO:PHOSPHOTHREONINE | ||
1fin | [AB] | [AB] | [AB] | 2.3 | ATP:ADENOSINE-5___sq___-TRIPHOSPHATE | ||
1fvv | [AB] | [AB] | [AB] | 2.8 | 107:4-[(7-OXO-7H-THIAZOLO[5,4-E]INDOL-8-YLMETHYL)-AMINO]-N-PYRIDIN-2-YL-BENZENESULFONAMIDE | ||
1gy3 | [AB][a] | [AB][a] | [AB][a] | 2.7 | ATP:ADENOSINE-5___sq___-TRIPHOSPHATE GOL:GLYCEROL MG:MAGNESIUM ION NO3:NITRATE ION TPO:PHOSPHOTHREONINE | ||
1h1p | [AB] | [AB] | [AB] | 2.1 | CMG:6-O-CYCLOHEXYLMETHYL GUANINE TPO:PHOSPHOTHREONINE | ||
1h1q | [AB] | [AB] | [AB] | 2.5 | 2A6:2-ANILINO-6-CYCLOHEXYLMETHOXYPURINE TPO:PHOSPHOTHREONINE | ||
1h1r | [AB] | [AB] | [AB] | 2 | 6CP:6-CYCLOHEXYLMETHOXY-2-(3___sq___-CHLOROANILINO) PURINE TPO:PHOSPHOTHREONINE | ||
1h1s | [AB] | [AB] | [AB] | 2 | 4SP:O6-CYCLOHEXYLMETHOXY-2-(4___sq___-SULPHAMOYLANILINO)PURINE TPO:PHOSPHOTHREONINE | ||
1h24 | [AB][a] | [AB][a] | [AB][a] | 2.5 | TPO:PHOSPHOTHREONINE | ||
1h25 | [AB][a] | [AB][a] | [AB][a] | 2.5 | TPO:PHOSPHOTHREONINE | ||
1h26 | [AB][a] | [AB][a] | [AB][a] | 2.24 | TPO:PHOSPHOTHREONINE | ||
1h27 | [AB][a] | [AB][a] | [AB][a] | 2.2 | TPO:PHOSPHOTHREONINE | ||
1h28 | [AB][a] | [AB][a] | [AB][a] | 2.8 | TPO:PHOSPHOTHREONINE | ||
1jst | [A2B2] | [A2B2] | [A2B2] | 2.6 | ATP:ADENOSINE-5___sq___-TRIPHOSPHATE MN:MANGANESE (II) ION TPO:PHOSPHOTHREONINE | ||
1jsu | ![]() |
[ABC] | [ABC] | [ABC] | 2.3 | SO4:SULFATE ION TPO:PHOSPHOTHREONINE | |
1ogu | [AB] | [AB] | [AB] | 2.6 | SGM:MONOTHIOGLYCEROL ST8:4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE TPO:PHOSPHOTHREONINE | ||
1oi9 | [AB] | [AB] | [AB] | 2.1 | MG:MAGNESIUM ION N20:6-CYCLOHEXYLMETHYLOXY-2-(4___sq___-HYDROXYANILINO)PURINE SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | ||
1oiu | [AB] | [AB] | [AB] | 2 | MG:MAGNESIUM ION N76:3-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDE SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | ||
1oiy | [AB] | [AB] | [AB] | 2.4 | MG:MAGNESIUM ION N41:4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | ||
1okv | [AB][a] | [AB][a] | [AB][a] | 2.4 | NH2:AMINO GROUP | ||
1okw | [AB][a] | [AB][a] | [AB][a] | 2.5 | ACE:ACETYL GROUP FCL:3-CHLORO-L-PHENYLALANINE NH2:AMINO GROUP | ||
1ol1 | [AB][a] | [AB][a] | [AB][a] | 2.9 | CIR:CITRULLINE NH2:AMINO GROUP PFF:4-FLUORO-L-PHENYLALANINE | ||
1ol2 | [AB][a] | [AB][a] | [AB][a] | 2.6 | NH2:AMINO GROUP PFF:4-FLUORO-L-PHENYLALANINE | ||
1p5e | [AB] | [AB] | [AB] | 2.22 | TBS:4,5,6,7-TETRABROMOBENZOTRIAZOLE TPO:PHOSPHOTHREONINE | ||
1pkd | [AB] | [AB] | [AB] | 2.3 | TPO:PHOSPHOTHREONINE UCN:7-HYDROXYSTAUROSPORINE | ||
1qmz | [A2B2][a2] | [A2B2][a2] | [A2B2][a2] | 2.2 | ATP:ADENOSINE-5___sq___-TRIPHOSPHATE MG:MAGNESIUM ION TPO:PHOSPHOTHREONINE | ||
1urc | [AB][a] | [AB][a] | [AB][a] | 2.6 | ACE:ACETYL GROUP | ||
1vyw | [AB] | [AB] | [AB] | 2.3 | 292:N-(3-CYCLOPROPYL-1H-PYRAZOL-5-YL)-2-(2-NAPHTHYL)ACETAMIDE SO4:SULFATE ION | ||
2bkz | [AB] | [AB] | [AB] | 2.6 | SBC:1-[4-(AMINOSULFONYL)PHENYL]-1,6-DIHYDROPYRAZOLO[3,4-E]INDAZOLE-3-CARBOXAMIDE SO4:SULFATE ION | ||
2bpm | [AB] | [AB] | [AB] | 2.4 | 529:(2S)-N-[(3Z)-5-CYCLOPROPYL-3H-PYRAZOL-3-YLIDENE]-2-[4-(2-OXOIMIDAZOLIDIN-1-YL)PHENYL]PROPANAMIDE SO4:SULFATE ION | ||
2c4g | [AB] | [AB] | [AB] | 2.7 | 514:(3Z)-5-ACETYL-3-(BENZOYLIMINO)-3,6-DIHYDROPYRROLO[3,4-C]PYRAZOL-5-IUM SO4:SULFATE ION | ||
2c5n | [AB] | [AB] | [AB] | 2.1 | CK8:N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N___sq___,N___sq___-DIMETHYL-BENZENE-1,4-DIAMINE | ||
2c5o | [AB] | [AB] | [AB] | 2.1 | CK2:4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)PYRIMIDIN-2-AMINE | ||
2c5v | [AB][a] | [AB][a] | [AB][a] | 2.9 | ABA:ALPHA-AMINOBUTYRIC ACID CK4:4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)-N-[4-(TRIFLUOROMETHYL)PHENYL]PYRIMIDIN-2-AMINE NH2:AMINO GROUP PFF:4-FLUORO-L-PHENYLALANINE | ||
2c5x | [AB] | [AB] | [AB] | 2.9 | MTW:HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM | ||
2c6t | [AB] | [AB] | [AB] | 2.61 | DT5:4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE TPO:PHOSPHOTHREONINE | ||
2cch | [AB][a] | [AB][a] | [AB][a] | 1.7 | ATP:ADENOSINE-5___sq___-TRIPHOSPHATE GOL:GLYCEROL SO4:SULFATE ION TPO:PHOSPHOTHREONINE | ||
2cci | ![]() |
[ABC] | [ABC] | [ABC] | 2.7 | ATP:ADENOSINE-5___sq___-TRIPHOSPHATE MG:MAGNESIUM ION TPO:PHOSPHOTHREONINE | |
2cjm | [AB] | [AB] | [AB] | 2.3 | ATP:ADENOSINE-5___sq___-TRIPHOSPHATE MG:MAGNESIUM ION PTR:O-PHOSPHOTYROSINE TPO:PHOSPHOTHREONINE | ||
2i40 | [AB] | [AB] | [AB] | 2.8 | BLZ:5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE | ||
2iw6 | ![]() |
[AB] | [AB] | [AB] | 2.3 | MG:MAGNESIUM ION QQ2:[(2-CHLORO-5-METHYLPHENYL){6-[(4-{[(2R)-3-(DIMETHYLAMINO)-2-HYDROXYPROPYL]OXY}PHENYL)AMINO]PYRIMIDIN-4-YL}AMINO]ACETONITRILE SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | |
2iw8 | ![]() |
[AB] | [AB] | [AB] | 2.3 | 4SP:O6-CYCLOHEXYLMETHOXY-2-(4___sq___-SULPHAMOYLANILINO)PURINE SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | |
2iw9 | ![]() |
[AB] | [AB] | [AB] | 2 | 4SP:O6-CYCLOHEXYLMETHOXY-2-(4___sq___-SULPHAMOYLANILINO)PURINE MG:MAGNESIUM ION SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | |
2uue | [AB][a] | [AB][a] | [AB][a] | 2.06 | GVC:1-(3,5-DICHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID MTZ:4-METHYL-5-{(2E)-2-[(4-MORPHOLIN-4-YLPHENYL)IMINO]-2,5-DIHYDROPYRIMIDIN-4-YL}-1,3-THIAZOL-2-AMINE NH2:AMINO GROUP PFF:4-FLUORO-L-PHENYLALANINE | ||
2uzb | [AB] | [AB] | [AB] | 2.7 | C75:4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-FURYL}-N-METHYLBENZENESULFONAMIDE TPO:PHOSPHOTHREONINE | ||
2uzd | [AB] | [AB] | [AB] | 2.72 | C85:4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE TPO:PHOSPHOTHREONINE | ||
2uze | [AB] | [AB] | [AB] | 2.4 | C95:4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZOIC ACID TPO:PHOSPHOTHREONINE | ||
2uzl | [AB] | [AB] | [AB] | 2.4 | C94:4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE TPO:PHOSPHOTHREONINE | ||
2v22 | [AB] | [AB] | [AB] | 2.6 | C35:N~2~-{[1-(4-CHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOL-3-YL]CARBONYL}-N~5~-(DIAMINOMETHYLIDENE)-L-ORNITHYL-L-LEUCYL-L-ISOLEUCYL-4-FLUORO-L-PHENYLALANINAMIDE | ||
2wev | [AB][a] | [AB][a] | [AB][a] | 2.3 | ACE:ACETYL GROUP B3L:(3S)-3-AMINO-5-METHYLHEXANOIC ACID CK7:[4-(2-AMINO-4-METHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-(3-NITRO-PHENYL)-AMINE MEA:N-METHYLPHENYLALANINE NH2:AMINO GROUP | ||
2wfy | [AB][a] | [AB][a] | [AB][a] | 2.53 | ACE:ACETYL GROUP B3L:(3S)-3-AMINO-5-METHYLHEXANOIC ACID NH2:AMINO GROUP | ||
2whb | [AB][a] | [AB][a] | [AB][a] | 2.9 | L3O:(2S,3S)-3-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID NH2:AMINO GROUP PFF:4-FLUORO-L-PHENYLALANINE | ||
2wih | [AB] | [AB] | [AB] | 2.5 | P48:N,1,4,4-TETRAMETHYL-8-{[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]AMINO}-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE SO4:SULFATE ION | ||
2wip | [AB] | [AB] | [AB] | 2.8 | P49:1-METHYL-8-(PHENYLAMINO)-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXYLIC ACID SO4:SULFATE ION | ||
2wpa | [AB] | [AB] | [AB] | 2.51 | 889:N-{6,6-DIMETHYL-5-[(1-METHYLPIPERIDIN-4-YL)CARBONYL]-1,4,5,6-TETRAHYDROPYRROLO[3,4-C]PYRAZOL-3-YL}-3-METHYLBUTANAMIDE SO4:SULFATE ION | ||
2wxv | [AB] | [AB] | [AB] | 2.6 | SO4:SULFATE ION WXV:N,1-DIMETHYL-8-{[1-(METHYLSULFONYL)PIPERIDIN-4-YL]AMINO}-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE | ||
3eid | [AB] | [AB] | [AB] | 3.15 | PO5:(2S)-1-(DIMETHYLAMINO)-3-(4-{[4-(6-MORPHOLIN-4-YLPYRAZOLO[1,5-B]PYRIDAZIN-3-YL)PYRIMIDIN-2-YL]AMINO}PHENOXY)PROPAN-2-OL | ||
3ej1 | [AB] | [AB] | [AB] | 3.22 | 5BP:N-CYCLOPROPYL-4-PYRAZOLO[1,5-B]PYRIDAZIN-3-YLPYRIMIDIN-2-AMINE | ||
3f5x | [A4B4] | [A4B4] | [A4B4] | 2.4 | EZV:4-{3-[7-(4-METHYLPIPERAZIN-1-YL)-1H-BENZIMIDAZOL-2-YL]-1H-INDAZOL-6-YL}ANILINE GOL:GLYCEROL SO4:SULFATE ION | ||
4cfm | [AB] | [AB] | [AB] | 2.85 | 4QE:6-(CYCLOHEXYLMETHOXY)-8-(2-METHYLPHENYL)-9H-PURIN-2-AMINE TPO:PHOSPHOTHREONINE | ||
4cfn | [AB] | [AB] | [AB] | 2.2 | DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE JYM:6-(CYCLOHEXYLMETHOXY)-8-(TRIFLUOROMETHYL)-9H-PURIN-2-AMINE TPO:PHOSPHOTHREONINE | ||
4cfw | [AB] | [AB] | [AB] | 2.45 | SQ9:3-[2-AMINO-6-(CYCLOHEXYLMETHOXY)-7H-PURIN-8-YL]-2-METHYLBENZENESULFONAMIDE TPO:PHOSPHOTHREONINE | ||
4eoi | ![]() |
[AB] | [AB] | [AB] | 2 | 1RO:(5E)-5-(QUINOLIN-6-YLMETHYLIDENE)-2-[(THIOPHEN-2-YLMETHYL)AMINO]-1,3-THIAZOL-4(5H)-ONE DMS:DIMETHYL SULFOXIDE SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | |
4eoj | ![]() |
[AB] | [AB] | [AB] | 1.65 | ATP:ADENOSINE-5___sq___-TRIPHOSPHATE MG:MAGNESIUM ION SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | |
4eok | ![]() |
[AB] | [AB] | [AB] | 2.57 | 4SP:O6-CYCLOHEXYLMETHOXY-2-(4___sq___-SULPHAMOYLANILINO) PURINE SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | |
4eol | ![]() |
[AB] | [AB] | [AB] | 2.4 | 1RO:(5E)-5-(QUINOLIN-6-YLMETHYLIDENE)-2-[(THIOPHEN-2-YLMETHYL)AMINO]-1,3-THIAZOL-4(5H)-ONE MG:MAGNESIUM ION SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | |
4eom | ![]() |
[AB] | [AB] | [AB] | 2.1 | ATP:ADENOSINE-5___sq___-TRIPHOSPHATE MG:MAGNESIUM ION TPO:PHOSPHOTHREONINE | |
4eon | ![]() |
[AB] | [AB] | [AB] | 2.4 | 1RO:(5E)-5-(QUINOLIN-6-YLMETHYLIDENE)-2-[(THIOPHEN-2-YLMETHYL)AMINO]-1,3-THIAZOL-4(5H)-ONE MG:MAGNESIUM ION TPO:PHOSPHOTHREONINE | |
4eoo | ![]() |
[AB] | [AB] | [AB] | 2.1 | ATP:ADENOSINE-5___sq___-TRIPHOSPHATE MG:MAGNESIUM ION SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | |
4eop | ![]() |
[AB] | [AB] | [AB] | 1.99 | 1RO:(5E)-5-(QUINOLIN-6-YLMETHYLIDENE)-2-[(THIOPHEN-2-YLMETHYL)AMINO]-1,3-THIAZOL-4(5H)-ONE MG:MAGNESIUM ION SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | |
4eoq | [AB] | [AB] | [AB] | 2.15 | ATP:ADENOSINE-5___sq___-TRIPHOSPHATE MG:MAGNESIUM ION SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | ||
4eor | [AB] | [AB] | [AB] | 2.2 | 4SP:O6-CYCLOHEXYLMETHOXY-2-(4___sq___-SULPHAMOYLANILINO) PURINE TPO:PHOSPHOTHREONINE | ||
4eos | [AB] | [AB] | [AB] | 2.57 | 1RO:(5E)-5-(QUINOLIN-6-YLMETHYLIDENE)-2-[(THIOPHEN-2-YLMETHYL)AMINO]-1,3-THIAZOL-4(5H)-ONE TPO:PHOSPHOTHREONINE | ||
4fx3 | [AB] | [AB] | [AB] | 2.75 | 60K:(3Z)-2-OXO-3-[2-(4-SULFAMOYLPHENYL)HYDRAZINYLIDENE]-2,3-DIHYDRO-1H-INDOLE-5-CARBOXYLIC ACID DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE | ||
5cyi | [AB] | [AB] | [AB] | 2 | 55S:6-(CYCLOHEXYLMETHOXY)-N-[4-(ETHYLSULFONYL)PHENYL]-9H-PURIN-2-AMINE TPO:PHOSPHOTHREONINE | ||
5if1 | [AB] | [AB] | [AB] | 2.61 | |||
5lmk | [AB] | [AB] | [AB] | 2.4 | 6ZK:4-[4-[3-BROMANYL-7-(PYRIDIN-3-YLMETHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDIN-5-YL]PHENYL]BENZAMIDE MG:MAGNESIUM ION SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | ||
5nev | [AB] | [AB] | [AB] | 2.97 | 72L:4-[[6-(3-PHENYLPHENYL)-7~{H}-PURIN-2-YL]AMINO]BENZENESULFONAMIDE TPO:PHOSPHOTHREONINE | ||
6ath | [ABC] | [ABC] | [ABC] | 1.82 | SO4:SULFATE ION TPO:PHOSPHOTHREONINE | ||
6gva | [AB] | [AB] | [AB] | 2.15 | BR:BROMIDE ION CL:CHLORIDE ION EDO:1,2-ETHANEDIOL FCQ:5-(2-AZANYLETHYLSULFANYL)-3-PROPAN-2-YL-~{N}-[(4-PYRIDIN-2-YLPHENYL)METHYL]-2~{H}-PYRAZOLO[4,3-D]PYRIMIDIN-7-AMINE PG4:TETRAETHYLENE GLYCOL PGE:TRIETHYLENE GLYCOL SGM:MONOTHIOGLYCEROL TPO:PHOSPHOTHREONINE | ||
6p3w | [AB][a] | [AB][a] | [AB][a] | 2.54 | PO4:PHOSPHATE ION | ||
6rij | [AB] | [AB] | [AB] | 2.2 | GOL:GLYCEROL K4W:4-[[[5-NITROSO-2-[[(2~{R})-1-OXIDANYLBUTAN-2-YL]AMINO]-6-(PROPAN-2-YLAMINO)PYRIMIDIN-4-YL]AMINO]METHYL]PHENOL NA:SODIUM ION TPO:PHOSPHOTHREONINE | ||
6sg4 | [A2B2] | [A2B2] | [A2B2] | 2.43 | TPO:PHOSPHOTHREONINE | ||
7ack | [AB] | [AB] | [AB] | 1.8 | EDO:1,2-ETHANEDIOL NA:SODIUM ION NO3:NITRATE ION R7B:8-CYCLOHEXYL-6~{H}-IMIDAZO[1,2-C]PYRIMIDIN-5-ONE TPO:PHOSPHOTHREONINE | ||
7luo | [A4] | [A4] | [A4] | 3.17 |
*Chain Formula of OLIGAMI.
[ ] : Polypeptide - [AB] : Protein, [ab] : Small peptide
( ) : Nucleic acid - (AB) : DNA, (ab) : RNA
[ ] : Polypeptide - [AB] : Protein, [ab] : Small peptide
( ) : Nucleic acid - (AB) : DNA, (ab) : RNA