Number of Chains

SCOPe

Number of Protein Chains:4

PDB Entries

PDB ID OPM Mutant Chain Formula Resolution HETNAM
Amino Acid sequence SCOPe Family Level CATH Homology Level
1i51 [A2B2C2] [A2B2C2] [A2B2C2] 2.45
2uvl [A2] [A2] [A2] 1.91
GOL:GLYCEROL
ZN:ZINC ION
2vsl [A][a] [A][a] [A][a] 2.1
15P:POLYETHYLENE GLYCOL (N=34)
MAA:N-METHYL-L-ALANINE
ZN:ZINC ION
3f7g [A] [A] [A] 2.3
389:L-ALANYL-L-VALYL-N-(2,2-DIPHENYLETHYL)-L-PROLINAMIDE
P33:3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL
ZN:ZINC ION
3f7h [A] [A] [A] 1.8
419:N-[(3AR,6S,6AS)-1-(N-METHYL-L-ALANYL-3-METHYL-L-VALYL)OCTAHYDROCYCLOPENTA[B]PYRROL-6-YL]-2,2-DIPHENYLACETAMIDE
BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
EDO:1,2-ETHANEDIOL
LI:LITHIUM ION
ZN:ZINC ION
3f7i [A] [A] [A] 1.9
BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
EDO:1,2-ETHANEDIOL
G13:N-[(3AR,6S,6AS)-1-(N-METHYL-L-ALANYL-3-METHYL-L-VALYL)OCTAHYDROCYCLOPENTA[B]PYRROL-6-YL]NAPHTHALENE-1-CARBOXAMIDE
LI:LITHIUM ION
ZN:ZINC ION
3g76 [A] [A] [A] 3
CZ3:1,1___sq___-{HEXA-2,4-DIYNE-1,6-DIYLBIS[OXY{(2S,3R)-2-[(N-METHYL-L-ALANYL)AMINO]-1-OXOBUTANE-3,1-DIYL}(2S)PYRROLIDINE-1,2-DIYLMETHANEDIYL]}BIS[5-(PHENYLSULFANYL)-1H-TETRAZOLE]
ZN:ZINC ION
3hl5 [A] [A] [A] 1.8
9JZ:(3S)-1-{(2S)-2-CYCLOHEXYL-2-[(N-METHYL-L-ALANYL)AMINO]ACETYL}-3-METHYL-N-(2-PYRIMIDIN-2-YLPHENYL)-L-PROLINAMIDE
ZN:ZINC ION
3mup [A4] [A4] [A4] 2.6
SMK:(3S,6S,7R,9AS)-6-{[(2S)-2-AMINOBUTANOYL]AMINO}-7-(2-AMINOETHYL)-N-(DIPHENYLMETHYL)-5-OXOOCTAHYDRO-1H-PYRROLO[1,2-A]AZEPINE-3-CARBOXAMIDE
ZN:ZINC ION
3uec [A2][a2] [A2][a2] [A2][a2] 2.18
1PE:PENTAETHYLENE GLYCOL
ACT:ACETATE ION
EDO:1,2-ETHANEDIOL
PEG:DI(HYDROXYETHYL)ETHER
PG4:TETRAETHYLENE GLYCOL
TPO:PHOSPHOTHREONINE
ZN:ZINC ION
3ued [A2][a2] [A2][a2] [A2][a2] 2.7
TPO:PHOSPHOTHREONINE
ZN:ZINC ION
3uee [A2][a2] [A2][a2] [A2][a2] 2.61
ZN:ZINC ION
3uef [A2][a2] [A2][a2] [A2][a2] 2.45
EDO:1,2-ETHANEDIOL
ZN:ZINC ION
3ueg [A2] [A2] [A2] 2.8
EDO:1,2-ETHANEDIOL
PG4:TETRAETHYLENE GLYCOL
ZN:ZINC ION
3ueh [A2] [A2] [A2] 2.6
EDO:1,2-ETHANEDIOL
PEG:DI(HYDROXYETHYL)ETHER
PGE:TRIETHYLENE GLYCOL
ZN:ZINC ION
3uei [A2] [A2] [A2] 2.7
ZN:ZINC ION
4a0n [A][a] [A][a] [A][a] 2.74
TPO:PHOSPHOTHREONINE
ZN:ZINC ION
4hy0 [A2] [A2] [A2] 2.84
1AQ:(3S,7R,8AR)-2-{(2S)-2-(4,4-DIFLUOROCYCLOHEXYL)-2-[(N-METHYL-L-ALANYL)AMINO]ACETYL}-N-[(4R)-3,4-DIHYDRO-2H-CHROMEN-4-YL]-7-ETHOXYOCTAHYDROPYRROLO[1,2-A]PYRAZINE-3-CARBOXAMIDE
ZN:ZINC ION
4hy4 [A] [A] [A] 1.25
1BG:(3S,8AR)-2-{(2S)-2-CYCLOHEXYL-2-[(N-METHYL-L-ALANYL)AMINO]ACETYL}-N-[(1R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL]OCTAHYDROPYRROLO[1,2-A]PYRAZINE-3-CARBOXAMIDE
ZN:ZINC ION
4hy5 [A] [A] [A] 1.75
1AQ:(3S,7R,8AR)-2-{(2S)-2-(4,4-DIFLUOROCYCLOHEXYL)-2-[(N-METHYL-L-ALANYL)AMINO]ACETYL}-N-[(4R)-3,4-DIHYDRO-2H-CHROMEN-4-YL]-7-ETHOXYOCTAHYDROPYRROLO[1,2-A]PYRAZINE-3-CARBOXAMIDE
ZN:ZINC ION
4kmp [A] [A] [A] 1.95
GT6:(2S,2___sq___S)-N,N___sq___-[(6,6___sq___-DIFLUORO-1H,1___sq___H-2,2___sq___-BIINDOLE-3,3___sq___-DIYL)BIS{METHANEDIYL[(2R,4S)-4-HYDROXYPYRROLIDINE-2,1-DIYL][(2S)-1-OXOBUTANE-1,2-DIYL]}]BIS[2-(METHYLAMINO)PROPANAMIDE]
ZN:ZINC ION
4lge [A] [A] [A] 1.55
1Y0:(4S,6AR,7AS)-5-{(2S)-2-CYCLOHEXYL-2-[(N-METHYL-L-ALANYL)AMINO]ACETYL}-N-[(4R)-3,4-DIHYDRO-2H-CHROMEN-4-YL]OCTAHYDRO-1H-CYCLOPROPA[4,5]PYRROLO[1,2-A]PYRAZINE-4-CARBOXAMIDE
ZN:ZINC ION
4lgu [A] [A] [A] 2
1YH:(3S,8AR)-N-((R)-CHROMAN-4-YL)-2-((S)-2-CYCLOHEXYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)ACETYL)OCTAHYDROPYRROLO[1,2-A]PYRAZINE-3-CARBOXAMIDE
ZN:ZINC ION
4mti [A] [A] [A] 2.15
2DX:(3S,8AR)-2-[(2S)-2-CYCLOHEXYL-2-{[(2S)-2-(METHYLAMINO)BUTANOYL]AMINO}ACETYL]-N-[(4R)-3,4-DIHYDRO-2H-CHROMEN-4-YL]OCTAHYDROPYRROLO[1,2-A]PYRAZINE-3-CARBOXAMIDE
ZN:ZINC ION
4mu7 [A] [A] [A] 1.79
2DY:(3S,10AS)-2-[(2S)-2-CYCLOHEXYL-2-{[(2S)-2-(METHYLAMINO)BUTANOYL]AMINO}ACETYL]-N-[(4R)-3,4-DIHYDRO-2H-CHROMEN-4-YL]-1,2,3,4,10,10A-HEXAHYDROPYRAZINO[1,2-A]INDOLE-3-CARBOXAMIDE
ZN:ZINC ION
5c0k [A] [A] [A] 2.2
4WK:(2S)-1-{[(2S)-1-AMINO-3-METHYL-1-OXOBUTAN-2-YL]AMINO}-1-OXOPROPAN-2-AMINIUM
EDO:1,2-ETHANEDIOL
ZN:ZINC ION
5c0l [A] [A] [A] 2.6
4WJ:4-(4-BROMO-1H-PYRAZOL-1-YL)PIPERIDINIUM
ZN:ZINC ION
5c3h [A] [A] [A] 2.65
4XE:4-[2-OXO-2-(PIPERIDIN-1-YL)ETHYL]PIPERAZIN-1-IUM
ZN:ZINC ION
5c3k [A] [A] [A] 2.02
4XF:(2S)-1-[(6-AMINOPYRIDIN-2-YL)AMINO]-1-OXOPROPAN-2-AMINIUM
ZN:ZINC ION
5c7a [A] [A] [A] 2.36
4YE:(2R)-4-[2-(2,3-DIHYDRO-1H-INDOL-1-YL)-2-OXOETHYL]-2-METHYLPIPERAZIN-1-IUM
ZN:ZINC ION
5c7b [A] [A] [A] 2.68
4YD:(2R)-2-METHYL-4-[2-OXO-2-(PYRROLIDIN-1-YL)ETHYL]PIPERAZIN-1-IUM
ZN:ZINC ION
5c7c [A] [A] [A] 2.32
4YC:(2R)-4-[2-(6-CHLORO-3,3-DIMETHYL-2,3-DIHYDRO-1H-INDOL-1-YL)-2-OXOETHYL]-2-METHYLPIPERAZIN-1-IUM
ZN:ZINC ION
5c7d [A] [A] [A] 2.25
4YF:(2R)-4-[2-(6-CHLORO-2,3-DIHYDRO-1H-PYRROLO[3,2-C]PYRIDIN-1-YL)-2-OXOETHYL]-2-METHYLPIPERAZIN-1-IUM
ZN:ZINC ION
5c83 [A] [A] [A] 2.33
4YN:(2R,5R)-4-[2-(6-BENZYL-3,3-DIMETHYL-2,3-DIHYDRO-1H-PYRROLO[3,2-C]PYRIDIN-1-YL)-2-OXOETHYL]-5-(METHOXYMETHYL)-2-METHYLPIPERAZIN-1-IUM
ZN:ZINC ION
5c84 [A] [A] [A] 2.36
4YL:(2R,5R)-4-[2-(6-CHLORO-3,3-DIMETHYL-2,3-DIHYDRO-1H-PYRROLO[3,2-C]PYRIDIN-1-YL)-2-OXOETHYL]-5-(METHOXYMETHYL)-2-METHYLPIPERAZIN-1-IUM
ZN:ZINC ION
5m6e [A] [A] [A] 2.32
7HT:1-[3,3-DIMETHYL-6-(PHENYLMETHYL)-2~{H}-PYRROLO[3,2-C]PYRIDIN-1-YL]-2-[(2~{R},5~{R})-5-METHYL-2-[(4-METHYLPYRAZOL-1-YL)METHYL]PIPERAZIN-4-IUM-1-YL]ETHANONE
DMS:DIMETHYL SULFOXIDE
NA:SODIUM ION
ZN:ZINC ION
5m6f [A] [A] [A] 2.39
7HU:1-[3,3-DIMETHYL-6-(PHENYLMETHYL)-2~{H}-PYRROLO[3,2-B]PYRIDIN-1-YL]-2-[(2~{R},5~{R})-2-(METHOXYMETHYL)-5-METHYL-PIPERAZIN-4-IUM-1-YL]ETHANONE
NA:SODIUM ION
ZN:ZINC ION
5m6h [A] [A] [A] 2.5
7J6:1-[3,3-DIMETHYL-6-(PHENYLMETHYL)-2~{H}-PYRROLO[3,2-B]PYRIDIN-1-YL]-2-[(2~{R},5~{R})-5-METHYL-2-MORPHOLIN-4-YLCARBONYL-PIPERAZIN-4-IUM-1-YL]ETHANONE
NA:SODIUM ION
ZN:ZINC ION
5m6l [A] [A] [A] 2.61
7H9:1-[6-[(4-FLUOROPHENYL)METHYL]-3,3-DIMETHYL-2~{H}-PYRROLO[3,2-B]PYRIDIN-1-YL]-2-[(2~{R},5~{R})-5-METHYL-2-[[(3~{R})-3-METHYLMORPHOLIN-4-YL]METHYL]PIPERAZIN-4-IUM-1-YL]ETHANONE
NA:SODIUM ION
ZN:ZINC ION
5m6m [A] [A] [A] 2.37
7H8:1-[[(2~{R},5~{R})-1-[2-[3,3-DIMETHYL-6-(PHENYLMETHYL)-2~{H}-PYRROLO[3,2-B]PYRIDIN-1-YL]-2-OXIDANYLIDENE-ETHYL]-5-METHYL-PIPERAZIN-4-IUM-2-YL]METHYL]PYRROLIDIN-2-ONE
NA:SODIUM ION
ZN:ZINC ION
5m6n [A] [A] [A] 1.8
7H9:1-[6-[(4-FLUOROPHENYL)METHYL]-3,3-DIMETHYL-2~{H}-PYRROLO[3,2-B]PYRIDIN-1-YL]-2-[(2~{R},5~{R})-5-METHYL-2-[[(3~{R})-3-METHYLMORPHOLIN-4-YL]METHYL]PIPERAZIN-4-IUM-1-YL]ETHANONE
SO4:SULFATE ION
ZN:ZINC ION
5oqw [A2] [A2] [A2] 2.31
A4E:1-[6-[(4-FLUOROPHENYL)METHYL]-5-(HYDROXYMETHYL)-3,3-DIMETHYL-2~{H}-PYRROLO[3,2-B]PYRIDIN-1-YL]-2-[(2~{R},5~{R})-5-METHYL-2-[[(3~{R})-3-METHYLMORPHOLIN-4-YL]METHYL]PIPERAZIN-4-IUM-1-YL]ETHANONE
NA:SODIUM ION
ZN:ZINC ION
6exw [A] [A] [A] 2.2
C3K:(3~{S},6~{S},7~{R},9~{A}~{S})-6-[[(2~{S})-2-(METHYLAMINO)PROPANOYL]AMINO]-5-OXIDANYLIDENE-~{N}-(PHENYLMETHYL)-7-[(PROPANOYLAMINO)METHYL]-3,6,7,8,9,9~{A}-HEXAHYDROPYRROLO[1,2-A]AZEPINE-3-CARBOXAMIDE
ZN:ZINC ION
6ey2 [A] [A] [A] 2.7
C3T:(3~{S},6~{S},7~{S},9~{A}~{S})-~{N}-[(4-~{TERT}-BUTYLPHENYL)METHYL]-7-(HYDROXYMETHYL)-6-[[(2~{S})-2-(METHYLAMINO)BUTANOYL]AMINO]-5-OXIDANYLIDENE-1,2,3,6,7,8,9,9~{A}-OCTAHYDROPYRROLO[1,2-A]AZEPINE-3-CARBOXAMIDE
ZN:ZINC ION
6h6q [A2] [A2] [A2] 2.63
FUK:2-[(2~{R},5~{R})-2-[[(3~{R},5~{R})-3,5-DIMETHYLMORPHOLIN-4-YL]METHYL]-5-METHYL-PIPERAZIN-1-YL]-1-[6-[(~{S})-(4-FLUOROPHENYL)-OXIDANYL-METHYL]-3,3-DIMETHYL-2~{H}-PYRROLO[3,2-B]PYRIDIN-1-YL]ETHANONE
ZN:ZINC ION
6h6r [A] [A] [A] 2.03
FUE:2-[[(2~{R},5~{R})-1-[2-[6-[(4-FLUOROPHENYL)METHYL]-3,3-DIMETHYL-2~{H}-PYRROLO[3,2-B]PYRIDIN-1-YL]-2-OXIDANYLIDENE-ETHYL]-5-METHYL-PIPERAZIN-2-YL]METHYL]-3~{H}-ISOINDOL-1-ONE
NA:SODIUM ION
ZN:ZINC ION
6w74 [A] [A] [A] 2.11
TKY:14-{[(3S)-2-(N-METHYL-L-ALANYL-3-METHYL-L-VALYL)-3-{[(1R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL]CARBAMOYL}-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL]OXY}-3,6,9,12-TETRAOXATETRADECAN-1-YL (3R)-3-{5-AMINO-4-CARBAMOYL-3-[4-(2,4-DIFLUOROPHENOXY)PHENYL]-1H-PYRAZOL-1-YL}PIPERIDINE-1-CARBOXYLATE
ZN:ZINC ION
6w7o [AB] [AB] [AB] 2.17
TL7:[5-({[(3S)-2-(N-METHYL-L-ALANYL-3-METHYL-L-VALYL)-3-{[(1R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL]CARBAMOYL}-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL]OXY}METHYL)PYRAZIN-2-YL]METHYL (3R)-3-{5-AMINO-4-CARBAMOYL-3-[4-(2,4-DIFLUOROPHENOXY)PHENYL]-1H-PYRAZOL-1-YL}PIPERIDINE-1-CARBOXYLATE
ZN:ZINC ION
*Chain Formula of OLIGAMI.
  [ ] : Polypeptide - [AB] : Protein, [ab] : Small peptide
  ( ) : Nucleic acid - (AB) : DNA, (ab) : RNA
PDL