Number of Protein Chains:12
- Classes: All alpha proteins
- Folds: SWIB/MDM2 domain
- Superfamilies: SWIB/MDM2 domain
- Families: automated matches
- Protein Domains: automated matches
- Species: Human (Homo sapiens) [TaxId: 9606]
PDB Entries
PDB ID | OPM | Mutant | Chain Formula | Resolution | HETNAM | ||
---|---|---|---|---|---|---|---|
Amino Acid sequence | SCOPe Family Level | CATH Homology Level | |||||
2n06 | [A] | [A] | [A] | SOLUTION NMR |
44Z:4-[[(4S,5R)-5-(4-CHLOROPHENYL)-4-(3-METHOXYPHENYL)-2-(4-METHOXY-2-PROPAN-2-YLOXY-PHENYL)-4,5-DIHYDROIMIDAZOL-1-YL]CARBONYL]PIPERAZIN-2-ONE | ||
2n0u | [A] | [A] | [A] | SOLUTION NMR |
48M:4-[(4S,5R)-4-(3-CHLOROPHENYL)-5-(4-CHLOROPHENYL)-1-(3-OXIDANYLIDENEPIPERAZIN-1-YL)CARBONYL-4,5-DIHYDROIMIDAZOL-2-YL]-3-PROPAN-2-YLOXY-BENZENECARBONITRILE | ||
2n0w | [A] | [A] | [A] | SOLUTION NMR |
48L:4-({(4S,5R)-4-(5-BROMO-2-FLUOROPHENYL)-5-(4-CHLOROPHENYL)-2-[4-METHOXY-2-(PROPAN-2-YLOXY)PHENYL]-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}CARBONYL)PIPERAZIN-2-ONE | ||
2n14 | [A] | [A] | [A] | SOLUTION NMR |
49H:4-({(4S,5R)-4-(3-CHLOROPHENYL)-5-(4-CHLOROPHENYL)-2-[4-METHOXY-2-(PROPAN-2-YLOXY)PHENYL]-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}CARBONYL)PIPERAZIN-2-ONE | ||
2vyr | [A8B4] | [A8B4] | [A8B4] | 2 | SO4:SULFATE ION | ||
3dab | [A][a] | [A][a] | [A][a] | 1.9 | |||
3fdo | [A] | [A] | [A] | 1.4 | MG:MAGNESIUM ION | ||
3fe7 | [A][a] | [A][a] | [A][a] | 1.35 | 1AC:1-AMINOCYCLOPROPANECARBOXYLIC ACID ACE:ACETYL GROUP AIB:ALPHA-AMINOISOBUTYRIC ACID NH2:AMINO GROUP PM3:2-AMINO-3-(4-PHOSPHONOMETHYL-PHENYL)-PROPIONIC ACID | ||
3fea | [A][a] | [A][a] | [A][a] | 1.33 | 1AC:1-AMINOCYCLOPROPANECARBOXYLIC ACID 6CW:6-CHLORO-L-TRYPTOPHAN ACE:ACETYL GROUP AIB:ALPHA-AMINOISOBUTYRIC ACID MPD:(4S)-2-METHYL-2,4-PENTANEDIOL NH2:AMINO GROUP PM3:2-AMINO-3-(4-PHOSPHONOMETHYL-PHENYL)-PROPIONIC ACID | ||
3jzo | [A][a] | [A][a] | [A][a] | 1.8 | K:POTASSIUM ION | ||
3jzp | [A][a] | [A][a] | [A][a] | 1.74 | K:POTASSIUM ION | ||
3jzq | [A][a] | [A][a] | [A][a] | 1.8 | SO4:SULFATE ION | ||
3lbj | [A] | [A] | [A] | 1.5 | SO4:SULFATE ION WW8:N-[(3S)-1-({6-CHLORO-3-[1-(4-CHLOROBENZYL)-4-PHENYL-1H-IMIDAZOL-5-YL]-1H-INDOL-2-YL}CARBONYL)PYRROLIDIN-3-YL]-N,N___sq___,N___sq___-TRIMETHYLPROPANE-1,3-DIAMINE | ||
3u15 | [A2] | [A2] | [A2] | 1.8 | 03M:(5Z)-5-[(6-CHLORO-7-METHYL-1H-INDOL-3-YL)METHYLIDENE]-3-(3,4-DIFLUOROBENZYL)IMIDAZOLIDINE-2,4-DIONE SO4:SULFATE ION | ||
6q9q | [A] | [A] | [A] | 2.1 | GOL:GLYCEROL HUE:6-CHLORANYL-3-[3-[(1~{S})-1-(4-CHLOROPHENYL)ETHYL]-5-PHENYL-IMIDAZOL-4-YL]-~{N}-[2-(4-CYCLOHEXYLPIPERAZIN-1-YL)ETHYL]-1~{H}-INDOLE-2-CARBOXAMIDE O4B:1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE SO4:SULFATE ION | ||
6q9s | [A] | [A] | [A] | 2.4 | HRN:3-[[6-CHLORANYL-3-[3-[(1~{S})-1-(2,4-DICHLOROPHENYL)ETHYL]-5-PHENYL-IMIDAZOL-4-YL]-1~{H}-INDOL-2-YL]CARBONYLAMINO]-4-[4-(2-OXIDANYLIDENE-1,3-OXAZINAN-3-YL)PIPERIDIN-1-YL]BENZOIC ACID NA:SODIUM ION O4B:1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE SO4:SULFATE ION | ||
6q9u | [A] | [A] | [A] | 2.4 | CL:CHLORIDE ION HRE:4-[(4~{S})-5-(5-CHLORANYL-2-OXIDANYLIDENE-1~{H}-PYRIDIN-3-YL)-2-[2-(DIMETHYLAMINO)-4-METHOXY-PYRIMIDIN-5-YL]-6-OXIDANYLIDENE-3-PROPAN-2-YL-4~{H}-PYRROLO[3,4-C]PYRAZOL-4-YL]BENZENECARBONITRILE O4B:1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE | ||
6q9w | [A] | [A] | [A] | 1.55 | HRT:(4~{S})-4-(4-CHLOROPHENYL)-5-[(1~{S})-1-(3-CHLOROPHENYL)ETHYL]-2-(2,4-DIMETHOXYPYRIMIDIN-5-YL)-3-PROPAN-2-YL-4~{H}-PYRROLO[3,4-D]IMIDAZOL-6-ONE O4B:1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE SO4:SULFATE ION | ||
6q9y | [A] | [A] | [A] | 1.2 | HRQ:7-METHOXY-~{N}-[(3~{S})-1-(4-METHYLPHENYL)PYRROLIDIN-3-YL]-1~{H}-INDOLE-3-CARBOXAMIDE | ||
7c3q | [A] | [A] | [A] | 1.8 | NUT:4-({(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-[4-METHOXY-2-(PROPAN-2-YLOXY)PHENYL]-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}CARBONYL)PIPERAZIN-2-ONE O4B:1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE PEG:DI(HYDROXYETHYL)ETHER | ||
7c3y | [A] | [A] | [A] | 1.63 | NUT:4-({(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-[4-METHOXY-2-(PROPAN-2-YLOXY)PHENYL]-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}CARBONYL)PIPERAZIN-2-ONE O4B:1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE | ||
7c44 | [A] | [A] | [A] | 1.65 | NUT:4-({(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-[4-METHOXY-2-(PROPAN-2-YLOXY)PHENYL]-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}CARBONYL)PIPERAZIN-2-ONE O4B:1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE |
*Chain Formula of OLIGAMI.
[ ] : Polypeptide - [AB] : Protein, [ab] : Small peptide
( ) : Nucleic acid - (AB) : DNA, (ab) : RNA
[ ] : Polypeptide - [AB] : Protein, [ab] : Small peptide
( ) : Nucleic acid - (AB) : DNA, (ab) : RNA