Number of Protein Chains:6
- Classes: Alpha and beta proteins (a/b)
- Folds: Subtilisin-like
- Superfamilies: Subtilisin-like
- Families: Subtilases
- Protein Domains: Proprotein convertase subtilisin/kexin type 9
- Species: Human (Homo sapiens) [TaxId: 9606]
PDB Entries
PDB ID | OPM | Mutant | Chain Formula | Resolution | HETNAM | ||
---|---|---|---|---|---|---|---|
Amino Acid sequence | SCOPe Family Level | CATH Homology Level | |||||
2p4e | [A] | [A] | [A] | 1.98 | HG:MERCURY (II) ION | ||
2qtw | [AB] | [AB] | [AB] | 1.9 | CA:CALCIUM ION NAG:2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE | ||
2w2m | [ABC] | [ABC] | [ABC] | 2.4 | CA:CALCIUM ION | ||
2w2n | [ABC] | [ABC] | [ABC] | 2.3 | CA:CALCIUM ION | ||
2w2o | [ABC] | [ABC] | [ABC] | 2.62 | CA:CALCIUM ION | ||
2w2p | [ABC] | [ABC] | [ABC] | 2.62 | CA:CALCIUM ION | ||
2w2q | [ABC] | [ABC] | [ABC] | 2.33 | CA:CALCIUM ION | ||
2xtj | [ABCDEF] | [A2BCDE] | [A4BC] | 2.7 | CA:CALCIUM ION | ||
3bps | [ABC] | [ABC] | [ABC] | 2.41 | CA:CALCIUM ION | ||
3gcw | [ABC] | [ABC] | [ABC] | 2.7 | CA:CALCIUM ION | ||
3sqo | [ABCD] | [ABCD] | [A2BC] | 2.7 | |||
4ne9 | [AB] | [AB] | [AB] | 2.6 | CA:CALCIUM ION FUC:ALPHA-L-FUCOPYRANOSE NAG:2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE | ||
4ov6 | [ABC] | [ABC] | [ABC] | 2.69 | EDO:1,2-ETHANEDIOL PG4:TETRAETHYLENE GLYCOL | ||
5oca | [ABCD] | [ABCD] | [ABCD] | 2.3 | NA:SODIUM ION TWA:2,3,4-TRI-O-SULFO-BETA-D-ALTROPYRANOSE TWD:2,3-DI-O-SULFO-ALPHA-L-GLUCOPYRANOSE | ||
6u26 | [A] | [A] | [A] | 1.53 | 063:4___sq___-{[(1R)-6-{2-[2-({N~5~-[N,N___sq___-BIS(TERT-BUTOXYCARBONYL)CARBAMIMIDOYL]-N~2~-(TERT-BUTOXYCARBONYL)-L-ORNITHYL}AMINO)ETHOXY]ETHOXY}-1-METHYL-1-{2-OXO-2-[(1,3-THIAZOL-2-YL)AMINO]ETHYL}-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL]OXY}-2___sq___-FLUORO[1,1___sq___-BIPHENYL]-4-CARBOXYLIC ACID | ||
6u2n | [A2] | [A2] | [A2] | 2.15 | PV7:4-{[(1R)-6-METHOXY-1-METHYL-1-{2-OXO-2-[(1,3-THIAZOL-2-YL)AMINO]ETHYL}-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL]OXY}BENZOIC ACID | ||
6u2p | [A2] | [A2] | [A2] | 2.04 | EDO:1,2-ETHANEDIOL PUV:2-FLUORO-4-{[(1R)-6-METHOXY-1-METHYL-1-{2-OXO-2-[(1,3-THIAZOL-2-YL)AMINO]ETHYL}-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL]OXY}BENZOIC ACID | ||
6u36 | [A2BC] | [A2BC] | [A2BC] | 2.7 | PVM:2-FLUORO-4-{[(1R)-6-(2-{4-[1-(4-METHOXYPHENYL)-5-METHYL-6-OXO-1,6-DIHYDROPYRIDAZIN-3-YL]-1H-1,2,3-TRIAZOL-1-YL}ETHOXY)-1-METHYL-1-{2-OXO-2-[(1,3-THIAZOL-2-YL)AMINO]ETHYL}-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL]OXY}BENZOIC ACID | ||
6u38 | [A2BC] | [A2BC] | [A2BC] | 2.73 | PVJ:2-FLUORO-4-{[(1R)-1-METHYL-6-{[(2S)-OXAN-2-YL]METHOXY}-1-{2-OXO-2-[(1,3-THIAZOL-2-YL)AMINO]ETHYL}-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL]OXY}BENZOIC ACID | ||
6u3x | [A2] | [A2] | [A2] | 2.64 | PVV:2-[(1R)-6,7-DIMETHOXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLIN-1-YL]-N-(1,3-THIAZOL-2-YL)ACETAMIDE |
*Chain Formula of OLIGAMI.
[ ] : Polypeptide - [AB] : Protein, [ab] : Small peptide
( ) : Nucleic acid - (AB) : DNA, (ab) : RNA
[ ] : Polypeptide - [AB] : Protein, [ab] : Small peptide
( ) : Nucleic acid - (AB) : DNA, (ab) : RNA