- Classes: Alpha and beta proteins (a/b)
- Folds: Dihydrofolate reductase-like
- Superfamilies: Dihydrofolate reductase-like
- Families: Dihydrofolate reductases
- Protein Domains: Dihydrofolate reductases, eukaryotic type
- Species: Fungus (Pneumocystis carinii) [TaxId: 4754]
PDB Entries
PDB ID | OPM | Mutant | Chain Formula | Resolution | HETNAM | |||
---|---|---|---|---|---|---|---|---|
Amino Acid sequence | SCOPe Family Level | CATH Homology Level | ||||||
1cd2 | [A] | [A] | [A] | 2.2 | FOL:FOLIC ACID NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | |||
1daj | [A] | [A] | [A] | 2.3 | MOT:N-[4-[(2,4-DIAMINOFURO[2,3D]PYRIMIDIN-5-YL)METHYL]METHYLAMINO]-BENZOYL]-L-GLUTAMATE NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE | |||
1dyr | [A] | [A] | [A] | 1.86 | NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE TOP:TRIMETHOPRIM | |||
1e26 | [A] | [A] | [A] | 2 | GPB:N-[4-[2-(2-AMINO-4-METHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYL]GLUTAMIC ACID NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | |||
1klk | [A] | [A] | [A] | 2.3 | NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE PMD:[N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE | |||
1ly3 | [A] | [A] | [A] | 1.9 | COG:2,4-DIAMINO-6-[N-(2___sq___,5___sq___-DIMETHOXYBENZYL)-N-METHYLAMINO]QUINAZOLINE NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | |||
1ly4 | [A] | [A] | [A] | 2.1 | COQ:2,4-DIAMINO-6-[N-(3___sq___,5___sq___-DIMETHOXYBENZYL)-N-METHYLAMINO]PYRIDO[2,3-D]PYRIMIDINE NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | |||
1s3y | [A] | [A] | [A] | 2.25 | NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE TQT:6-(OCTAHYDRO-1H-INDOL-1-YLMETHYL)DECAHYDROQUINAZOLINE-2,4-DIAMINE | |||
1vj3 | [A] | [A] | [A] | 2.1 | NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE TAB:ACETIC ACID N-[2-CHLORO-5-[6-ETHYL-2,4-DIAMINO-PYRIMID-5-YL]-PHENYL]-[BENZYL-TRIAZEN-3-YL]ETHYL ESTER | |||
2cd2 | [A] | [A] | [A] | 1.9 | FOL:FOLIC ACID NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | |||
2fzh | [A] | [A] | [A] | 2.1 | DH1:2,4-DIAMINO-5-[2-METHOXY-5-(4-CARBOXYBUTYLOXY)BENZYL]PYRIMIDINE NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE | |||
2fzi | [A] | [A] | [A] | 1.6 | DH3:2,4-DIAMINO-5-[3___sq___,4___sq___-DIMETHOXY-5___sq___-(5-CARBOXYL-1-PENTYNYL)]BENZYL PYRIMIDINE NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE | |||
3cd2 | [A] | [A] | [A] | 2.5 | MTX:METHOTREXATE NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | |||
3nz6 | [A] | [A] | [A] | 2 | D2J:6-{3-[(2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDIN-6-YL)METHYL]-4-METHOXYPHENOXY}HEXANOIC ACID NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE | |||
3nz9 | [A] | [A] | [A] | 1.8 | D2K:ETHYL 4-{3-[(2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDIN-6-YL)METHYL]-4-METHOXYPHENOXY}BUTANOATE NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE | |||
3nza | [A] | [A] | [A] | 1.9 | CL:CHLORIDE ION D2K:ETHYL 4-{3-[(2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDIN-6-YL)METHYL]-4-METHOXYPHENOXY}BUTANOATE NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE | |||
3nzb | [A] | [A] | [A] | 1.45 | D2N:ETHYL 6-{3-[(2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDIN-6-YL)METHYL]-4-METHOXYPHENOXY}HEXANOATE NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE | |||
3nzc | [A] | [A] | [A] | 2 | D2O:6-[2-METHOXY-5-(2-PHENYLETHOXY)BENZYL]-5-METHYLPYRIDO[2,3-D]PYRIMIDINE-2,4-DIAMINE GOL:GLYCEROL PO4:PHOSPHATE ION | |||
4cd2 | [A] | [A] | [A] | 2 | FOL:FOLIC ACID |
*Chain Formula of OLIGAMI.
[ ] : Polypeptide - [AB] : Protein, [ab] : Small peptide
( ) : Nucleic acid - (AB) : DNA, (ab) : RNA
[ ] : Polypeptide - [AB] : Protein, [ab] : Small peptide
( ) : Nucleic acid - (AB) : DNA, (ab) : RNA