PDB ID : 1efl [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

Style





Secondary Structure


Download

Slab plane

Direction Proportion
From front %
From back %
Move slab

Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CC
DD
Title
HUMAN MALIC ENZYME IN A QUATERNARY COMPLEX WITH NAD, MG, AND TARTRONATE

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
1efl
10700286 X-RAY DIFFRACTION/2.6 MG:MAGNESIUM ION
MSE:SELENOMETHIONINE
NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE
TTN:TARTRONATE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
33943 A:21-279Alpha and beta proteins (a/b)Aminoacid dehydrogenase-like, N-terminal domainAminoacid dehydrogenase-like, N-terminal domainMalic enzyme N-domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
30295 A:280-573Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsAminoacid dehydrogenase-like, C-terminal domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
33944 B:21-279Alpha and beta proteins (a/b)Aminoacid dehydrogenase-like, N-terminal domainAminoacid dehydrogenase-like, N-terminal domainMalic enzyme N-domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
30296 B:280-573Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsAminoacid dehydrogenase-like, C-terminal domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
33945 C:21-279Alpha and beta proteins (a/b)Aminoacid dehydrogenase-like, N-terminal domainAminoacid dehydrogenase-like, N-terminal domainMalic enzyme N-domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
30297 C:280-573Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsAminoacid dehydrogenase-like, C-terminal domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
33946 D:21-279Alpha and beta proteins (a/b)Aminoacid dehydrogenase-like, N-terminal domainAminoacid dehydrogenase-like, N-terminal domainMalic enzyme N-domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
30298 D:280-573Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsAminoacid dehydrogenase-like, C-terminal domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]

CATH
CATH ID Node Class Architecture Topology Homology
1eflA013.40.50.10380:3-Layer(aba) Sandwich:Rossmann fold:Malic enzyme, N-terminal domain
1eflA023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1eflB013.40.50.10380:3-Layer(aba) Sandwich:Rossmann fold:Malic enzyme, N-terminal domain
1eflB023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1eflC013.40.50.10380:3-Layer(aba) Sandwich:Rossmann fold:Malic enzyme, N-terminal domain
1eflC023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1eflD013.40.50.10380:3-Layer(aba) Sandwich:Rossmann fold:Malic enzyme, N-terminal domain
1eflD023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain