OLIGAMI : Oligomer Architecture and Molecular Interface

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Title

MALIC ENZYME FROM PIGEON LIVER

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
1gq2			11790843	X-RAY DIFFRACTION/2.5	CL:CHLORIDE ION MN:MANGANESE (II) ION MSE:SELENOMETHIONINE NA:SODIUM ION NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE OXL:OXALATE ION

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A4]	[A4]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
70309	A:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70308	A:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70311	B:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70310	B:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70313	C:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70312	C:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70315	D:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70314	D:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70317	E:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70316	E:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70319	F:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70318	F:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70321	G:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70320	G:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70323	H:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70322	H:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70325	I:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70324	I:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70327	J:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70326	J:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70329	K:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70328	K:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70331	L:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70330	L:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70333	M:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70332	M:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70335	N:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70334	N:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70337	O:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70336	O:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70339	P:23-279	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Malic enzyme N-domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]
70338	P:280-580	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Mitochondrial NAD(P)-dependent malic enzyme	Domestic pigeon (Columba livia) [TaxId: 8932]

CATH

CATH ID	Node	Architecture	Topology	Homology
1gq2A01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2A02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2B01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2B02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2C01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2C02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2D01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2D02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2E01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2E02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2F01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2F02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2G01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2G02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2H01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2H02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2I01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2I02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2J01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2J02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2K01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2K02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2L01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2L02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2M01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2M02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2N01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2N02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2O01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2O02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1gq2P01	3.40.50.10380	:3-Layer(aba) Sandwich	:Rossmann fold	:Malic enzyme, N-terminal domain
1gq2P02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D

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