PDB ID : 1gyp [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

Style





Secondary Structure


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Slab plane

Direction Proportion
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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CC
DD
Title
CRYSTAL STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM LEISHMANIA MEXICANA: IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN AND A NEW POSITION FOR THE INORGANIC PHOSPHATE BINDING SITE

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
1gyp
7578111 X-RAY DIFFRACTION/2.8 NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE
PO4:PHOSPHATE ION
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
30004 A:1-165
A:335-358		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosome (Leishmania mexicana) [TaxId: 5665]
39919 A:166-334Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainGAPDH-likeGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosome (Leishmania mexicana) [TaxId: 5665]
30005 B:1-165
B:335-358		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosome (Leishmania mexicana) [TaxId: 5665]
39920 B:166-334Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainGAPDH-likeGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosome (Leishmania mexicana) [TaxId: 5665]
30006 C:1-165
C:335-358		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosome (Leishmania mexicana) [TaxId: 5665]
39921 C:166-334Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainGAPDH-likeGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosome (Leishmania mexicana) [TaxId: 5665]
30007 D:1-165
D:335-358		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosome (Leishmania mexicana) [TaxId: 5665]
39922 D:166-334Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainGAPDH-likeGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosome (Leishmania mexicana) [TaxId: 5665]

CATH
CATH ID Node Class Architecture Topology Homology
1gypA013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1gypA023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
1gypB013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1gypB023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
1gypC013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1gypC023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
1gypD013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1gypD023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2