PDB ID : 1gz4 [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

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Secondary Structure


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Slab plane

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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CC
DD
Title
MOLECULAR MECHANISM OF THE REGULATION OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME BY ATP AND FUMARATE

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
1gz4
12121650 X-RAY DIFFRACTION/2.2 ATP:ADENOSINE-5___sq___-TRIPHOSPHATE
FUM:FUMARIC ACID
MN:MANGANESE (II) ION
MSE:SELENOMETHIONINE
TTN:TARTRONATE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
70795 A:23-279Alpha and beta proteins (a/b)Aminoacid dehydrogenase-like, N-terminal domainAminoacid dehydrogenase-like, N-terminal domainMalic enzyme N-domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
70794 A:280-573Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsAminoacid dehydrogenase-like, C-terminal domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
70797 B:23-279Alpha and beta proteins (a/b)Aminoacid dehydrogenase-like, N-terminal domainAminoacid dehydrogenase-like, N-terminal domainMalic enzyme N-domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
70796 B:280-573Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsAminoacid dehydrogenase-like, C-terminal domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
70799 C:23-279Alpha and beta proteins (a/b)Aminoacid dehydrogenase-like, N-terminal domainAminoacid dehydrogenase-like, N-terminal domainMalic enzyme N-domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
70798 C:280-573Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsAminoacid dehydrogenase-like, C-terminal domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
70801 D:23-279Alpha and beta proteins (a/b)Aminoacid dehydrogenase-like, N-terminal domainAminoacid dehydrogenase-like, N-terminal domainMalic enzyme N-domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
70800 D:280-573Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsAminoacid dehydrogenase-like, C-terminal domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]

CATH
CATH ID Node Class Architecture Topology Homology
1gz4A013.40.50.10380:3-Layer(aba) Sandwich:Rossmann fold:Malic enzyme, N-terminal domain
1gz4A023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1gz4B013.40.50.10380:3-Layer(aba) Sandwich:Rossmann fold:Malic enzyme, N-terminal domain
1gz4B023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1gz4C013.40.50.10380:3-Layer(aba) Sandwich:Rossmann fold:Malic enzyme, N-terminal domain
1gz4C023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1gz4D013.40.50.10380:3-Layer(aba) Sandwich:Rossmann fold:Malic enzyme, N-terminal domain
1gz4D023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain