OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 1hwy [A6]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

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Secondary Structure

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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D
E	E
F	F

Title

BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH NAD AND 2-OXOGLUTARATE

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
1hwy			11254391	X-RAY DIFFRACTION/3.2	AKG:2-OXOGLUTARIC ACID NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE PO4:PHOSPHATE ION

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A6]	[A6]	[A6]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
33910	A:1-208	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Cow (Bos taurus) [TaxId: 9913]
30262	A:209-501	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Cow (Bos taurus) [TaxId: 9913]
33911	B:1-208	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Cow (Bos taurus) [TaxId: 9913]
30263	B:209-501	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Cow (Bos taurus) [TaxId: 9913]
33912	C:1-208	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Cow (Bos taurus) [TaxId: 9913]
30264	C:209-501	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Cow (Bos taurus) [TaxId: 9913]
33913	D:1-208	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Cow (Bos taurus) [TaxId: 9913]
30265	D:209-501	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Cow (Bos taurus) [TaxId: 9913]
33914	E:1-208	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Cow (Bos taurus) [TaxId: 9913]
30266	E:209-501	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Cow (Bos taurus) [TaxId: 9913]
33915	F:1-208	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Cow (Bos taurus) [TaxId: 9913]
30267	F:209-501	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Cow (Bos taurus) [TaxId: 9913]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
1hwyA01	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1hwyA02	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1hwyA03	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1hwyB01	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1hwyB02	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1hwyB03	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1hwyC01	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1hwyC02	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1hwyC03	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1hwyD01	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1hwyD02	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1hwyD03	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1hwyE01	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1hwyE02	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1hwyE03	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1hwyF01	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1hwyF02	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1hwyF03	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain