OLIGAMI : Oligomer Architecture and Molecular Interface

Title

STRUCTURE OF COENZYME F420H2:NADP+ OXIDOREDUCTASE (FNO) WITH ITS SUBSTRATES BOUND

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
1jay			11726492	X-RAY DIFFRACTION/1.65	F42:COENZYME F420 NA:SODIUM ION NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A2]	[A2]	[A2]

Interfaces

Interface ID	Chain	Inaterface Class	Interface Type	Contact Type
1jay_AB	A B	HEN_iE HEN_iE	i1_CR(H11,E9,N15)_CE(H3,E3,N5)_HH(S1)_EE(Ah1,iE1)_HE(S2)_HN(L1,S4)_EN(L1,S4) i1_CR(H11,E9,N15)_CE(H3,E3,N5)_HH(S1)_EE(Ah1,iE1)_HE(S2)_HN(L1,S4)_EN(L1,S4)	c4_RP(HH20,EE17,NN18,HE11,HN14,NE6,EH11,NH14,EN6)_HH(P1,A1,S1)_HE(P1,A2,S2)_HN(L2,S8)_EN(L1,S5) c4_RP(HH20,EE17,NN18,HE11,HN14,NE6,EH11,NH14,EN6)_HH(P1,A1,S1)_HE(P1,A2,S2)_HN(L2,S8)_EN(L1,S5)

Interface Class

Interface ID	Interface 1						Interface 2
	Domain	Number of contact residues	Binding site Class	Percentages of Secondary structures(%)			Domain	Number of contact residues	Binding site Class	Percentages of Secondary structures(%)
	Domain	Number of contact residues	Binding site Class	H	E	N	Domain	Number of contact residues	Binding site Class	H	E	N
1jay_AB	A	34	HEN_iE	38.2	100	32.4	B	34	HEN_iE	35.3	35.3	29.4

Interface Type: Information for each interface

Interface ID	chain	Number of contact residues			Number of elements					Number of contacts between Secondary structure elements
		Number of contact residues			Number of elements					HH			EE						HE			HN		EN
		Hn	En	Nn	H	E	N	R	L	P	A	S	P	A	S	Ph	Ah	Ih	P	A	S	L	S	L	S
1jay_AB	A	13	34	11	4	3	6	0	0	0	0	1	2	0	0	1	0	1	0	0	6	1	5	1	5
1jay_AB	B	12	12	10	3	4	6	0	0	0	0	1	2	0	0	1	0	1	0	0	7	1	5	1	6

Contact Type: Information of contacts between interfaces

Interface ID	Number of residue pairs between SS elements									Number of contacts between Secondary structure elements
	H-H	E-E	N-N	H-E	H-N	N-E	E-H	N-H	E-N	H-H				E-E					H-E				H-N			E-N
	H-H	E-E	N-N	H-E	H-N	N-E	E-H	N-H	E-N	P	A	S	Ih	P	A	S	IPh	IAh	P	A	S	Ih	L	S	Ih	L	S	Ih
1jay_AB	13	5	12	16	6	8	17	5	9	0	2	3	0	0	0	0	0	1	0	2	5	0	0	7	0	0	9	0

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
66478	A:	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase-like, N-terminal domain	Coenzyme F420H2:NADP+ oxidoreductase (FNO)	Archaeoglobus fulgidus [TaxId: 2234]
66479	B:	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase-like, N-terminal domain	Coenzyme F420H2:NADP+ oxidoreductase (FNO)	Archaeoglobus fulgidus [TaxId: 2234]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
1jayA00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1jayB00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain