PDB ID : 1k3t [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

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Secondary Structure


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Slab plane

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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CC
DD
Title
STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM TRYPANOSOMA CRUZI COMPLEXED WITH CHALEPIN, A COUMARIN DERIVATIVE INHIBITOR

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
1k3t
12044862 X-RAY DIFFRACTION/1.95 BRZ:6-(1,1-DIMETHYLALLYL)-2-(1-HYDROXY-1-METHYLETHYL)-2,3-DIHYDRO-7H-FURO[3,2-G]CHROMEN-7-ONE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
72022 A:1-164
A:334-359		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosoma cruzi [TaxId: 5693]
72023 A:165-333Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainGAPDH-likeGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosoma cruzi [TaxId: 5693]
72024 B:1-164
B:334-359		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosoma cruzi [TaxId: 5693]
72025 B:165-333Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainGAPDH-likeGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosoma cruzi [TaxId: 5693]
72026 C:1-164
C:334-359		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosoma cruzi [TaxId: 5693]
72027 C:165-333Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainGAPDH-likeGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosoma cruzi [TaxId: 5693]
72028 D:1-164
D:334-359		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosoma cruzi [TaxId: 5693]
72029 D:165-333Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainGAPDH-likeGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Trypanosoma cruzi [TaxId: 5693]

CATH
CATH ID Node Class Architecture Topology Homology
1k3tA013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1k3tA023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
1k3tB013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1k3tB023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
1k3tC013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1k3tC023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
1k3tD013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1k3tD023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2