OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 1l1f [A6]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

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Secondary Structure

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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D
E	E
F	F

Title

STRUCTURE OF HUMAN GLUTAMATE DEHYDROGENASE-APO FORM

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
1l1f			12054821	X-RAY DIFFRACTION/2.7

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A6]	[A6]	[A6]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
73457	A:10-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
73456	A:213-505	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
73459	B:10-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
73458	B:213-505	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
73461	C:10-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
73460	C:213-505	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
73463	D:10-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
73462	D:213-505	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
73465	E:10-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
73464	E:213-505	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
73467	F:10-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
73466	F:213-505	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
1l1fA01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1l1fA02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1l1fA03	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1l1fB01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1l1fB02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1l1fB03	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1l1fC01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1l1fC02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1l1fC03	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1l1fD01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1l1fD02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1l1fD03	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1l1fE01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1l1fE02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1l1fE03	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1l1fF01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1l1fF02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1l1fF03	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	: