OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 1li4 [A4]

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Title

HUMAN S-ADENOSYLHOMOCYSTEINE HYDROLASE COMPLEXED WITH NEPLANOCIN

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
1li4			12590576	X-RAY DIFFRACTION/2.01	IPA:ISOPROPYL ALCOHOL NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE NOC:3-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-CYCLOPENTANE-1,2-DIOL

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A4]	[A4]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
84616	A:190-352	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Formate/glycerate dehydrogenases, NAD-domain	S-adenosylhomocystein hydrolase	Human (Homo sapiens) [TaxId: 9606]
84617	A:3-189 A:353-432	Alpha and beta proteins (a/b)	Flavodoxin-like	Formate/glycerate dehydrogenase catalytic domain-like	S-adenosylhomocystein hydrolase	S-adenosylhomocystein hydrolase	Human (Homo sapiens) [TaxId: 9606]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
1li4A01	3.40.50.1480		:3-Layer(aba) Sandwich	:Rossmann fold	:Adenosylhomocysteinase-like
1li4A02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain