PDB ID : 1lth [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

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Secondary Structure


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Slab plane

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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AT
BT
CT
DT
Title
T AND R STATES IN THE CRYSTALS OF BACTERIAL L-LACTATE DEHYDROGENASE REVEAL THE MECHANISM FOR ALLOSTERIC CONTROL

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
1lth
7656036 X-RAY DIFFRACTION/2.5 FBP:1,6-DI-O-PHOSPHONO-BETA-D-FRUCTOFURANOSE
NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE
OXM:OXAMIC ACID
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
42146 R:150-319Alpha and beta proteins (a+b)LDH C-terminal domain-likeLDH C-terminal domain-likeLactate & malate dehydrogenases, C-terminal domainLactate dehydrogenaseBifidobacterium longum, strain am101-2 [TaxId: 216816]
30179 R:7-149Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsLDH N-terminal domain-likeLactate dehydrogenaseBifidobacterium longum, strain am101-2 [TaxId: 216816]
42147 T:150-319Alpha and beta proteins (a+b)LDH C-terminal domain-likeLDH C-terminal domain-likeLactate & malate dehydrogenases, C-terminal domainLactate dehydrogenaseBifidobacterium longum, strain am101-2 [TaxId: 216816]
30180 T:7-149Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsLDH N-terminal domain-likeLactate dehydrogenaseBifidobacterium longum, strain am101-2 [TaxId: 216816]

CATH
CATH ID Node Class Architecture Topology Homology
1lthR013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1lthR023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
1lthT013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1lthT023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal