OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 1np3 [A12]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Style

Secondary Structure

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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D
E	A
F	B
G	C
H	D
I	A
J	B
K	C
L	D

Title

CRYSTAL STRUCTURE OF CLASS I ACETOHYDROXY ACID ISOMEROREDUCTASE FROM PSEUDOMONAS AERUGINOSA

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
1np3			12691757	X-RAY DIFFRACTION/2

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A12]	[A12]	[A12]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
85947	A:1-182	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase-like, N-terminal domain	Class I ketol-acid reductoisomerase (KARI)	Pseudomonas aeruginosa [TaxId: 287]
85946	A:183-327	All alpha proteins	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)	Class I ketol-acid reductoisomerase	Pseudomonas aeruginosa [TaxId: 287]
85949	B:1-182	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase-like, N-terminal domain	Class I ketol-acid reductoisomerase (KARI)	Pseudomonas aeruginosa [TaxId: 287]
85948	B:183-327	All alpha proteins	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)	Class I ketol-acid reductoisomerase	Pseudomonas aeruginosa [TaxId: 287]
85951	C:1-182	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase-like, N-terminal domain	Class I ketol-acid reductoisomerase (KARI)	Pseudomonas aeruginosa [TaxId: 287]
85950	C:183-327	All alpha proteins	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)	Class I ketol-acid reductoisomerase	Pseudomonas aeruginosa [TaxId: 287]
85953	D:1-182	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase-like, N-terminal domain	Class I ketol-acid reductoisomerase (KARI)	Pseudomonas aeruginosa [TaxId: 287]
85952	D:183-327	All alpha proteins	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)	Class I ketol-acid reductoisomerase	Pseudomonas aeruginosa [TaxId: 287]

CATH

CATH ID	Node	Architecture	Topology	Homology
1np3A01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1np3A02	6.10.240.10	:Helix non-globular	:ProC C-terminal domain-like fold	:
1np3B01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1np3B02	6.10.240.10	:Helix non-globular	:ProC C-terminal domain-like fold	:
1np3C01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1np3C02	6.10.240.10	:Helix non-globular	:ProC C-terminal domain-like fold	:
1np3D01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1np3D02	6.10.240.10	:Helix non-globular	:ProC C-terminal domain-like fold	: