OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 1nr1 [A6]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
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^a AR:All Residues
^b IR:Interface Residues

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Secondary Structure

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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D
E	E
F	F

Title

CRYSTAL STRUCTURE OF THE R463A MUTANT OF HUMAN GLUTAMATE DEHYDROGENASE

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
1nr1			12653548	X-RAY DIFFRACTION/3.3

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A6]	[A6]	[A6]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
86081	A:10-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
86080	A:213-505	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
86083	B:10-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
86082	B:213-505	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
86085	C:10-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
86084	C:213-505	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
86087	D:10-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
86086	D:213-505	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
86089	E:10-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
86088	E:213-505	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
86091	F:10-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]
86090	F:213-505	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Human (Homo sapiens) [TaxId: 9606]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
1nr1A01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1nr1A02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1nr1A03	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1nr1B01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1nr1B02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1nr1B03	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1nr1C01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1nr1C02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1nr1C03	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1nr1D01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1nr1D02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1nr1D03	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1nr1E01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1nr1E02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1nr1E03	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
1nr1F01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
1nr1F02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1nr1F03	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	: