PDB ID : 1p44 [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

Style





Secondary Structure


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Slab plane

Direction Proportion
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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CA
DB
Title
TARGETING TUBERCULOSIS AND MALARIA THROUGH INHIBITION OF ENOYL REDUCTASE: COMPOUND ACTIVITY AND STRUCTURAL DATA

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
1p44
12606558 X-RAY DIFFRACTION/2.7 GEQ:5-{[4-(9H-FLUOREN-9-YL)PIPERAZIN-1-YL]CARBONYL}-1H-INDOLE
NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
94076 A:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
94077 B:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
94078 C:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
94079 D:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
94080 E:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
94081 F:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]

CATH
CATH ID Node Class Architecture Topology Homology
1p44A003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1p44B003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1p44C003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1p44D003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1p44E003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1p44F003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain