PDB ID : 1pj4 [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

Style





Secondary Structure


Download

Slab plane

Direction Proportion
From front %
From back %
Move slab

Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CC
DD
Title
CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE MALATE, ATP, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE.

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
1pj4
12962632 X-RAY DIFFRACTION/2.3 ATP:ADENOSINE-5___sq___-TRIPHOSPHATE
FUM:FUMARIC ACID
MLT:MALATE ION
MN:MANGANESE (II) ION
MSE:SELENOMETHIONINE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
94735 A:22-279Alpha and beta proteins (a/b)Aminoacid dehydrogenase-like, N-terminal domainAminoacid dehydrogenase-like, N-terminal domainMalic enzyme N-domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
94734 A:280-573Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsAminoacid dehydrogenase-like, C-terminal domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
94737 B:1022-1279Alpha and beta proteins (a/b)Aminoacid dehydrogenase-like, N-terminal domainAminoacid dehydrogenase-like, N-terminal domainMalic enzyme N-domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
94736 B:1280-1573Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsAminoacid dehydrogenase-like, C-terminal domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
94739 C:2022-2279Alpha and beta proteins (a/b)Aminoacid dehydrogenase-like, N-terminal domainAminoacid dehydrogenase-like, N-terminal domainMalic enzyme N-domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
94738 C:2280-2573Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsAminoacid dehydrogenase-like, C-terminal domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
94741 D:3022-3279Alpha and beta proteins (a/b)Aminoacid dehydrogenase-like, N-terminal domainAminoacid dehydrogenase-like, N-terminal domainMalic enzyme N-domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]
94740 D:3280-3573Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsAminoacid dehydrogenase-like, C-terminal domainMitochondrial NAD(P)-dependent malic enzymeHuman (Homo sapiens) [TaxId: 9606]

CATH
CATH ID Node Class Architecture Topology Homology
1pj4A013.40.50.10380:3-Layer(aba) Sandwich:Rossmann fold:Malic enzyme, N-terminal domain
1pj4A023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1pj4B013.40.50.10380:3-Layer(aba) Sandwich:Rossmann fold:Malic enzyme, N-terminal domain
1pj4B023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1pj4C013.40.50.10380:3-Layer(aba) Sandwich:Rossmann fold:Malic enzyme, N-terminal domain
1pj4C023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1pj4D013.40.50.10380:3-Layer(aba) Sandwich:Rossmann fold:Malic enzyme, N-terminal domain
1pj4D023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain