OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 1pzh [A4]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Style

Secondary Structure

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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D

Title

T.GONDII LDH1 TERNARY COMPLEX WITH NAD AND OXALATE

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
1pzh			14744130	X-RAY DIFFRACTION/1.9	NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE OXL:OXALATE ION

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A4]	[A4]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
95433	A:14-163	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Toxoplasma gondii [TaxId: 5811]
95434	A:164-333	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Toxoplasma gondii [TaxId: 5811]
282241	A:334-335	Artifacts	Tags	Tags	Tags	C-terminal Tags	Synthetic
95435	B:14-163	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Toxoplasma gondii [TaxId: 5811]
95436	B:164-333	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Toxoplasma gondii [TaxId: 5811]
282242	B:334-335	Artifacts	Tags	Tags	Tags	C-terminal Tags	Synthetic
95437	C:14-163	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Toxoplasma gondii [TaxId: 5811]
95438	C:164-332	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Toxoplasma gondii [TaxId: 5811]
95439	D:14-163	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Toxoplasma gondii [TaxId: 5811]
95440	D:164-332	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Toxoplasma gondii [TaxId: 5811]

CATH

CATH ID	Node	Architecture	Topology	Homology
1pzhA01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1pzhA02	3.90.110.10	:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
1pzhB01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1pzhB02	3.90.110.10	:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
1pzhC01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1pzhC02	3.90.110.10	:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
1pzhD01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1pzhD02	3.90.110.10	:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal