PDB ID : 1r4n [ABC]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

Style





Secondary Structure


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Slab plane

Direction Proportion
From front %
From back %
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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CI
Title
APPBP1-UBA3-NEDD8, AN E1-UBIQUITIN-LIKE PROTEIN COMPLEX WITH ATP

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
1r4n
14690597 X-RAY DIFFRACTION/3.6 ATP:ADENOSINE-5___sq___-TRIPHOSPHATE
ZN:ZINC ION
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[ABC] [A2B] [A2B]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
97011 A:Alpha and beta proteins (a/b)Activating enzymes of the ubiquitin-like proteinsActivating enzymes of the ubiquitin-like proteinsUbiquitin activating enzymes (UBA)Amyloid beta precursor protein-binding protein 1, APPBP1Human (Homo sapiens) [TaxId: 9606]
97012 B:Alpha and beta proteins (a/b)Activating enzymes of the ubiquitin-like proteinsActivating enzymes of the ubiquitin-like proteinsUbiquitin activating enzymes (UBA)UBA3Human (Homo sapiens) [TaxId: 9606]
97013 C:Alpha and beta proteins (a/b)Activating enzymes of the ubiquitin-like proteinsActivating enzymes of the ubiquitin-like proteinsUbiquitin activating enzymes (UBA)Amyloid beta precursor protein-binding protein 1, APPBP1Human (Homo sapiens) [TaxId: 9606]
97014 D:Alpha and beta proteins (a/b)Activating enzymes of the ubiquitin-like proteinsActivating enzymes of the ubiquitin-like proteinsUbiquitin activating enzymes (UBA)UBA3Human (Homo sapiens) [TaxId: 9606]
97015 E:Alpha and beta proteins (a/b)Activating enzymes of the ubiquitin-like proteinsActivating enzymes of the ubiquitin-like proteinsUbiquitin activating enzymes (UBA)Amyloid beta precursor protein-binding protein 1, APPBP1Human (Homo sapiens) [TaxId: 9606]
97016 F:Alpha and beta proteins (a/b)Activating enzymes of the ubiquitin-like proteinsActivating enzymes of the ubiquitin-like proteinsUbiquitin activating enzymes (UBA)UBA3Human (Homo sapiens) [TaxId: 9606]
97017 G:Alpha and beta proteins (a/b)Activating enzymes of the ubiquitin-like proteinsActivating enzymes of the ubiquitin-like proteinsUbiquitin activating enzymes (UBA)Amyloid beta precursor protein-binding protein 1, APPBP1Human (Homo sapiens) [TaxId: 9606]
97018 H:Alpha and beta proteins (a/b)Activating enzymes of the ubiquitin-like proteinsActivating enzymes of the ubiquitin-like proteinsUbiquitin activating enzymes (UBA)UBA3Human (Homo sapiens) [TaxId: 9606]
97019 I:Alpha and beta proteins (a+b)beta-Grasp (ubiquitin-like)Ubiquitin-likeUbiquitin-relatedNedd8Human (Homo sapiens) [TaxId: 9606]
97020 J:Alpha and beta proteins (a+b)beta-Grasp (ubiquitin-like)Ubiquitin-likeUbiquitin-relatedNedd8Human (Homo sapiens) [TaxId: 9606]
97021 K:Alpha and beta proteins (a+b)beta-Grasp (ubiquitin-like)Ubiquitin-likeUbiquitin-relatedNedd8Human (Homo sapiens) [TaxId: 9606]
97022 L:Alpha and beta proteins (a+b)beta-Grasp (ubiquitin-like)Ubiquitin-likeUbiquitin-relatedNedd8Human (Homo sapiens) [TaxId: 9606]

CATH
CATH ID Node Class Architecture Topology Homology
1r4nA013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1r4nB013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1r4nB021.10.10.520:Orthogonal Bundle:Arc Repressor Mutant, subunit A:Ubiquitin activating enzymes (Uba3). Chain: B, domain 2
1r4nB033.10.20.260:Roll:Ubiquitin-like (UB roll):NEDD8-activating enzyme E1, catalytic subunit
1r4nC013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1r4nD013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1r4nD021.10.10.520:Orthogonal Bundle:Arc Repressor Mutant, subunit A:Ubiquitin activating enzymes (Uba3). Chain: B, domain 2
1r4nD033.10.20.260:Roll:Ubiquitin-like (UB roll):NEDD8-activating enzyme E1, catalytic subunit
1r4nE013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1r4nF013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1r4nF021.10.10.520:Orthogonal Bundle:Arc Repressor Mutant, subunit A:Ubiquitin activating enzymes (Uba3). Chain: B, domain 2
1r4nF033.10.20.260:Roll:Ubiquitin-like (UB roll):NEDD8-activating enzyme E1, catalytic subunit
1r4nG013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1r4nH013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1r4nH021.10.10.520:Orthogonal Bundle:Arc Repressor Mutant, subunit A:Ubiquitin activating enzymes (Uba3). Chain: B, domain 2
1r4nH033.10.20.260:Roll:Ubiquitin-like (UB roll):NEDD8-activating enzyme E1, catalytic subunit
1r4nI003.10.20.90:Roll:Ubiquitin-like (UB roll):Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
1r4nJ003.10.20.90:Roll:Ubiquitin-like (UB roll):Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
1r4nK003.10.20.90:Roll:Ubiquitin-like (UB roll):Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
1r4nL003.10.20.90:Roll:Ubiquitin-like (UB roll):Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1