PDB ID : 1w0c [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

Style





Secondary Structure


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Slab plane

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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CC
DD
Title
INHIBITION OF LEISHMANIA MAJOR PTERIDINE REDUCTASE (PTR1) BY 2,4,6-TRIAMINOQUINAZOLINE; STRUCTURE OF THE NADP TERNARY COMPLEX.

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
1w0c
15388924 X-RAY DIFFRACTION/2.6 NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE
TAQ:2,4,6-TRIAMINOQUINAZOLINE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
114052 A:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesDihydropteridin reductase (pteridine reductase)Leishmania major [TaxId: 5664]
114053 B:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesDihydropteridin reductase (pteridine reductase)Leishmania major [TaxId: 5664]
114054 C:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesDihydropteridin reductase (pteridine reductase)Leishmania major [TaxId: 5664]
114055 D:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesDihydropteridin reductase (pteridine reductase)Leishmania major [TaxId: 5664]
114056 E:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesDihydropteridin reductase (pteridine reductase)Leishmania major [TaxId: 5664]
114057 F:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesDihydropteridin reductase (pteridine reductase)Leishmania major [TaxId: 5664]
114058 G:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesDihydropteridin reductase (pteridine reductase)Leishmania major [TaxId: 5664]
114059 H:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesDihydropteridin reductase (pteridine reductase)Leishmania major [TaxId: 5664]

CATH
CATH ID Node Class Architecture Topology Homology
1w0cA003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1w0cB003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1w0cC003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1w0cD003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1w0cE003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1w0cF003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1w0cG003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1w0cH003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain