PDB ID : 1xiv [A4]
Color
ARa IRb
|
|
a AR:All Residues
b IR:Interface Residues
b IR:Interface Residues
Slab plane
Title
PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE COMPLEXED WITH 2-({4- CHLORO-[HYDROXY(METHOXY)METHYL]CYCLOHEXYL}AMINO)ETHANE-1,1,2-TRIOL
Structure Summary
| PDB ID | Mutant | OPM | Pub Med | Method/Resolution | HETNAM |
|---|---|---|---|---|---|
| 1xiv | 15978953 | X-RAY DIFFRACTION/1.7 | GOL:GLYCEROL RB2:2-({4-CHLORO-2-[HYDROXY(METHOXY)METHYL]CYCLOHEXYL}AMINO)ETHANE-1,1,2-TRIOL |
| Chain Formula | ||
|---|---|---|
| Amino Acid sequence | SCOPe Family Level | CATH Homology Level |
| [A4] | [A4] | [A4] |
Structual Classification
SCOPe
| SCOPe ID | Chain | Class | Fold | Superfamily | Family | Protein Domain | Species |
|---|---|---|---|---|---|---|---|
| 122019 | A:165-329 | Alpha and beta proteins (a+b) | LDH C-terminal domain-like | LDH C-terminal domain-like | Lactate & malate dehydrogenases, C-terminal domain | automated matches | Malaria parasite (Plasmodium falciparum) [TaxId: 5833] |
| 122018 | A:18-164 | Alpha and beta proteins (a/b) | NAD(P)-binding Rossmann-fold domains | NAD(P)-binding Rossmann-fold domains | LDH N-terminal domain-like | automated matches | Malaria parasite (Plasmodium falciparum) [TaxId: 5833] |
| 284372 | A:330-332 | Artifacts | Tags | Tags | Tags | C-terminal Tags | Synthetic |
CATH
| CATH ID | Node | Class | Architecture | Topology | Homology |
|---|---|---|---|---|---|
| 1xivA01 | 3.40.50.720 | :3-Layer(aba) Sandwich | :Rossmann fold | :NAD(P)-binding Rossmann-like Domain | |
| 1xivA02 | 3.90.110.10 | :Alpha-Beta Complex | :L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2 | :Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal |
