OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 1xr3 [A4]

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Title

ACTINORHODIN POLYKETIDE KETOREDUCTASE WITH NADP AND THE INHIBITOR ISONIAZID BOUND

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
1xr3			15544323	X-RAY DIFFRACTION/2.71	ISZ:4-(DIAZENYLCARBONYL)PYRIDINE NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A4]	[A4]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
122245	A:6-261	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Tyrosine-dependent oxidoreductases	beta-keto acyl carrier protein reductase	Streptomyces coelicolor [TaxId: 1902]
122246	B:	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Tyrosine-dependent oxidoreductases	beta-keto acyl carrier protein reductase	Streptomyces coelicolor [TaxId: 1902]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
1xr3A00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1xr3B00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain