OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 1xwf [A4]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Style

Secondary Structure

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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D

Title

K185N MUTATED S-ADENOSYLHOMOCYSTEINE HYDROLASE

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
1xwf			16061414	X-RAY DIFFRACTION/2.8	ADN:ADENOSINE NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A4]	[A4]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
122392	A:190-352	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Formate/glycerate dehydrogenases, NAD-domain	S-adenosylhomocystein hydrolase	Norway rat (Rattus norvegicus) [TaxId: 10116]
122393	A:2-189 A:353-431	Alpha and beta proteins (a/b)	Flavodoxin-like	Formate/glycerate dehydrogenase catalytic domain-like	S-adenosylhomocystein hydrolase	S-adenosylhomocystein hydrolase	Norway rat (Rattus norvegicus) [TaxId: 10116]
122394	B:190-352	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Formate/glycerate dehydrogenases, NAD-domain	S-adenosylhomocystein hydrolase	Norway rat (Rattus norvegicus) [TaxId: 10116]
122395	B:2-189 B:353-431	Alpha and beta proteins (a/b)	Flavodoxin-like	Formate/glycerate dehydrogenase catalytic domain-like	S-adenosylhomocystein hydrolase	S-adenosylhomocystein hydrolase	Norway rat (Rattus norvegicus) [TaxId: 10116]
122396	C:190-352	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Formate/glycerate dehydrogenases, NAD-domain	S-adenosylhomocystein hydrolase	Norway rat (Rattus norvegicus) [TaxId: 10116]
122397	C:2-189 C:353-431	Alpha and beta proteins (a/b)	Flavodoxin-like	Formate/glycerate dehydrogenase catalytic domain-like	S-adenosylhomocystein hydrolase	S-adenosylhomocystein hydrolase	Norway rat (Rattus norvegicus) [TaxId: 10116]
122398	D:190-352	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Formate/glycerate dehydrogenases, NAD-domain	S-adenosylhomocystein hydrolase	Norway rat (Rattus norvegicus) [TaxId: 10116]
122399	D:2-189 D:353-431	Alpha and beta proteins (a/b)	Flavodoxin-like	Formate/glycerate dehydrogenase catalytic domain-like	S-adenosylhomocystein hydrolase	S-adenosylhomocystein hydrolase	Norway rat (Rattus norvegicus) [TaxId: 10116]

CATH

CATH ID	Node	Architecture	Topology	Homology
1xwfA01	3.40.50.1480	:3-Layer(aba) Sandwich	:Rossmann fold	:Adenosylhomocysteinase-like
1xwfA02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1xwfB01	3.40.50.1480	:3-Layer(aba) Sandwich	:Rossmann fold	:Adenosylhomocysteinase-like
1xwfB02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1xwfC01	3.40.50.1480	:3-Layer(aba) Sandwich	:Rossmann fold	:Adenosylhomocysteinase-like
1xwfC02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
1xwfD01	3.40.50.1480	:3-Layer(aba) Sandwich	:Rossmann fold	:Adenosylhomocysteinase-like
1xwfD02	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain