PDB ID : 1yl7 [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

Style





Secondary Structure


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Slab plane

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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CC
DD
Title
THE CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS DIHYDRODIPICOLINATE REDUCTASE (RV2773C) IN COMPLEX WITH NADH (CRYSTAL FORM C)

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
1yl7
20057050 X-RAY DIFFRACTION/2.34 MG:MAGNESIUM ION
NAI:1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
284702 A:1-1ArtifactsTagsTagsTagsN-terminal TagsSynthetic
123626 A:106-214Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainDihydrodipicolinate reductase-likeDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
123625 A:2-105
A:215-245		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
284703 B:1-1ArtifactsTagsTagsTagsN-terminal TagsSynthetic
123628 B:106-214Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainDihydrodipicolinate reductase-likeDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
123627 B:2-105
B:215-245		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
284704 C:1-1ArtifactsTagsTagsTagsN-terminal TagsSynthetic
123630 C:106-214Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainDihydrodipicolinate reductase-likeDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
123629 C:2-105
C:215-245		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
284705 D:1-1ArtifactsTagsTagsTagsN-terminal TagsSynthetic
123632 D:106-214Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainDihydrodipicolinate reductase-likeDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
123631 D:2-105
D:215-245		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
284706 E:1-1ArtifactsTagsTagsTagsN-terminal TagsSynthetic
123634 E:106-214Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainDihydrodipicolinate reductase-likeDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
123633 E:2-105
E:215-245		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
284707 F:1-1ArtifactsTagsTagsTagsN-terminal TagsSynthetic
123636 F:106-214Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainDihydrodipicolinate reductase-likeDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
123635 F:2-105
F:215-245		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
284708 G:1-1ArtifactsTagsTagsTagsN-terminal TagsSynthetic
123638 G:106-214Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainDihydrodipicolinate reductase-likeDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
123637 G:2-105
G:215-245		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
284709 H:1-1ArtifactsTagsTagsTagsN-terminal TagsSynthetic
123640 H:106-214Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainDihydrodipicolinate reductase-likeDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]
123639 H:2-105
H:215-245		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainDihydrodipicolinate reductaseMycobacterium tuberculosis [TaxId: 1773]

CATH
CATH ID Node Class Architecture Topology Homology
1yl7A013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1yl7A023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
1yl7B013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1yl7B023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
1yl7C013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1yl7C023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
1yl7D013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1yl7D023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
1yl7E013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1yl7E023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
1yl7F013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1yl7F023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
1yl7G013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1yl7G023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
1yl7H013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
1yl7H023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2