OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 2aa3 [A4]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Style

Secondary Structure

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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D

Title

CRYSTAL STRUCTURE OF PLASMODIUM VIVAX LACTATE DEHYDROGENASE COMPLEX WITH APADH

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
2aa3			16331982	X-RAY DIFFRACTION/2.05	AP0:ACETYL PYRIDINE ADENINE DINUCLEOTIDE, REDUCED SO4:SULFATE ION

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A4]	[A4]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
203423	A:164-329	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Plasmodium vivax [TaxId: 5855]
203422	A:18-163	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Plasmodium vivax [TaxId: 5855]
285152	A:330-330	Artifacts	Tags	Tags	Tags	C-terminal Tags	Synthetic
203425	B:164-329	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Plasmodium vivax [TaxId: 5855]
203424	B:18-163	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Plasmodium vivax [TaxId: 5855]
203427	C:164-329	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Plasmodium vivax [TaxId: 5855]
203426	C:18-163	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Plasmodium vivax [TaxId: 5855]
285153	C:330-332	Artifacts	Tags	Tags	Tags	C-terminal Tags	Synthetic
203429	D:164-329	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Plasmodium vivax [TaxId: 5855]
203428	D:18-163	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Plasmodium vivax [TaxId: 5855]

CATH

CATH ID	Node	Architecture	Topology	Homology
2aa3A01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2aa3A02	3.90.110.10	:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
2aa3B01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2aa3B02	3.90.110.10	:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
2aa3C01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2aa3C02	3.90.110.10	:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
2aa3D01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2aa3D02	3.90.110.10	:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal