OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 2ag5 [A4]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Style

Secondary Structure

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Slab plane

Direction	Proportion
From front	%
From back	%
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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D

Title

CRYSTAL STRUCTURE OF HUMAN DHRS6

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
2ag5			16380372	X-RAY DIFFRACTION/1.84	NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE SO4:SULFATE ION

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A4]	[A4]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
126719	A:1-245	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Tyrosine-dependent oxidoreductases	Dehydrogenase/reductase SDR family member 6, DHRS6	Human (Homo sapiens) [TaxId: 9606]
285200	A:246-246	Artifacts	Tags	Tags	Tags	C-terminal Tags	Synthetic
126720	B:2-245	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Human (Homo sapiens) [TaxId: 9606]
285201	B:246-246	Artifacts	Tags	Tags	Tags	C-terminal Tags	Synthetic
126721	C:	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Human (Homo sapiens) [TaxId: 9606]
126722	D:	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Human (Homo sapiens) [TaxId: 9606]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
2ag5A00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2ag5B00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2ag5C00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2ag5D00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain