OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 2amf [A10]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Style

Secondary Structure

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Slab plane

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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D
E	E
F	A
G	B
H	C
I	D
J	E

Title

CRYSTAL STRUCTURE OF 1-PYRROLINE-5-CARBOXYLATE REDUCTASE FROM HUMAN PATHOGEN STREPTOCOCCUS PYOGENES

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
2amf			16233902	X-RAY DIFFRACTION/2.2	NA:SODIUM ION PRO:PROLINE

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A10]	[A10]	[A10]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
285239	A:0-0	Artifacts	Tags	Tags	Tags	N-terminal Tags	Synthetic
127010	A:1-152	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase-like, N-terminal domain	Pyrroline-5-carboxylate reductase ProC	Streptococcus pyogenes [TaxId: 1314]
127009	A:153-256	All alpha proteins	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	ProC C-terminal domain-like	Pyrroline-5-carboxylate reductase ProC	Streptococcus pyogenes [TaxId: 1314]
285240	B:0-0	Artifacts	Tags	Tags	Tags	N-terminal Tags	Synthetic
127012	B:1-152	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase-like, N-terminal domain	Pyrroline-5-carboxylate reductase ProC	Streptococcus pyogenes [TaxId: 1314]
127011	B:153-256	All alpha proteins	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	ProC C-terminal domain-like	Pyrroline-5-carboxylate reductase ProC	Streptococcus pyogenes [TaxId: 1314]
127014	C:1-152	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase-like, N-terminal domain	Pyrroline-5-carboxylate reductase ProC	Streptococcus pyogenes [TaxId: 1314]
127013	C:153-256	All alpha proteins	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	ProC C-terminal domain-like	Pyrroline-5-carboxylate reductase ProC	Streptococcus pyogenes [TaxId: 1314]
285241	D:-1-0	Artifacts	Tags	Tags	Tags	N-terminal Tags	Synthetic
127016	D:1-152	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase-like, N-terminal domain	Pyrroline-5-carboxylate reductase ProC	Streptococcus pyogenes [TaxId: 1314]
127015	D:153-256	All alpha proteins	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	ProC C-terminal domain-like	Pyrroline-5-carboxylate reductase ProC	Streptococcus pyogenes [TaxId: 1314]
285242	E:-2-0	Artifacts	Tags	Tags	Tags	N-terminal Tags	Synthetic
127018	E:1-152	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase-like, N-terminal domain	Pyrroline-5-carboxylate reductase ProC	Streptococcus pyogenes [TaxId: 1314]
127017	E:153-256	All alpha proteins	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	ProC C-terminal domain-like	Pyrroline-5-carboxylate reductase ProC	Streptococcus pyogenes [TaxId: 1314]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
2amfA01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2amfA02	1.10.3730.10		:Orthogonal Bundle	:ProC C-terminal domain-like fold	:ProC C-terminal domain-like
2amfB01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2amfB02	1.10.3730.10		:Orthogonal Bundle	:ProC C-terminal domain-like fold	:ProC C-terminal domain-like
2amfC01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2amfC02	1.10.3730.10		:Orthogonal Bundle	:ProC C-terminal domain-like fold	:ProC C-terminal domain-like
2amfD01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2amfD02	1.10.3730.10		:Orthogonal Bundle	:ProC C-terminal domain-like fold	:ProC C-terminal domain-like
2amfE01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2amfE02	1.10.3730.10		:Orthogonal Bundle	:ProC C-terminal domain-like fold	:ProC C-terminal domain-like