PDB ID : 2b4t [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

Style





Secondary Structure


Download

Slab plane

Direction Proportion
From front %
From back %
Move slab

Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AO
BP
CQ
DR
Title
CRYSTAL STRUCTURE OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM PLASMODIUM FALCIPARUM AT 2.25 ANGSTROM RESOLUTION REVEALS INTRIGUING EXTRA ELECTRON DENSITY IN THE ACTIVE SITE

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
2b4t
16345073 X-RAY DIFFRACTION/2.5 AES:4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE
NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
127857 O:153-318Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainGAPDH-likeGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
285378 O:336-336ArtifactsTagsTagsTagsC-terminal TagsSynthetic
127856 O:4-152
O:319-335		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
127859 P:153-318Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainGAPDH-likeGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
285379 P:336-336ArtifactsTagsTagsTagsC-terminal TagsSynthetic
127858 P:4-152
P:319-335		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
127861 Q:153-318Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainGAPDH-likeGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
285380 Q:336-336ArtifactsTagsTagsTagsC-terminal TagsSynthetic
127860 Q:4-152
Q:319-335		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
127863 R:153-318Alpha and beta proteins (a+b)FwdE/GAPDH domain-likeGlyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainGAPDH-likeGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
285381 R:336-336ArtifactsTagsTagsTagsC-terminal TagsSynthetic
127862 R:4-152
R:319-335		Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsGlyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domainGlyceraldehyde-3-phosphate dehydrogenase (GAPDH)Malaria parasite (Plasmodium falciparum) [TaxId: 5833]

CATH
CATH ID Node Class Architecture Topology Homology
2b4tO013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2b4tO023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
2b4tP013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2b4tP023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
2b4tQ013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2b4tQ023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2
2b4tR013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2b4tR023.30.360.10:2-Layer Sandwich:Dihydrodipicolinate Reductase; domain 2:Dihydrodipicolinate Reductase; domain 2