PDB ID : 2cvz [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

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Secondary Structure


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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CC
DD
Title
STRUCTURE OF HYDROXYISOBUTYRATE DEHYDROGENASE FROM THERMUS THERMOPHILUS HB8

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
2cvz
16126223 X-RAY DIFFRACTION/1.8 MSE:SELENOMETHIONINE
NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
130890 A:158-289All alpha proteins6-phosphogluconate dehydrogenase C-terminal domain-like6-phosphogluconate dehydrogenase C-terminal domain-likeHydroxyisobutyrate and 6-phosphogluconate dehydrogenase domainHydroxyisobutyrate dehydrogenaseThermus thermophilus [TaxId: 274]
130891 A:2-157Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domains6-phosphogluconate dehydrogenase-like, N-terminal domainHydroxyisobutyrate dehydrogenaseThermus thermophilus [TaxId: 274]
130892 B:158-289All alpha proteins6-phosphogluconate dehydrogenase C-terminal domain-like6-phosphogluconate dehydrogenase C-terminal domain-likeHydroxyisobutyrate and 6-phosphogluconate dehydrogenase domainHydroxyisobutyrate dehydrogenaseThermus thermophilus [TaxId: 274]
130893 B:2-157Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domains6-phosphogluconate dehydrogenase-like, N-terminal domainHydroxyisobutyrate dehydrogenaseThermus thermophilus [TaxId: 274]
130894 C:158-289All alpha proteins6-phosphogluconate dehydrogenase C-terminal domain-like6-phosphogluconate dehydrogenase C-terminal domain-likeHydroxyisobutyrate and 6-phosphogluconate dehydrogenase domainHydroxyisobutyrate dehydrogenaseThermus thermophilus [TaxId: 274]
130895 C:2-157Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domains6-phosphogluconate dehydrogenase-like, N-terminal domainHydroxyisobutyrate dehydrogenaseThermus thermophilus [TaxId: 274]
130896 D:158-289All alpha proteins6-phosphogluconate dehydrogenase C-terminal domain-like6-phosphogluconate dehydrogenase C-terminal domain-likeHydroxyisobutyrate and 6-phosphogluconate dehydrogenase domainHydroxyisobutyrate dehydrogenaseThermus thermophilus [TaxId: 274]
130897 D:2-157Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domains6-phosphogluconate dehydrogenase-like, N-terminal domainHydroxyisobutyrate dehydrogenaseThermus thermophilus [TaxId: 274]

CATH
CATH ID Node Class Architecture Topology Homology
2cvzA013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2cvzA021.10.1040.10:Orthogonal Bundle:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
2cvzB013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2cvzB021.10.1040.10:Orthogonal Bundle:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
2cvzC013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2cvzC021.10.1040.10:Orthogonal Bundle:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
2cvzD013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2cvzD021.10.1040.10:Orthogonal Bundle:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2