OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 2fr0 [A]

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Title

THE FIRST KETOREDUCTASE OF THE ERYTHROMYCIN SYNTHASE (CRYSTAL FORM 1)

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
2fr0			16564177	X-RAY DIFFRACTION/1.81	NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A]	[A]	[A]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
133960	A:1448-1656	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Tyrosine-dependent oxidoreductases	Erythromycin synthase, eryAI, 1st ketoreductase module, N-terminal domain	Saccharopolyspora erythraea [TaxId: 1836]
133959	A:1657-1915	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Tyrosine-dependent oxidoreductases	Erythromycin synthase, eryAI, 1st ketoreductase module, C-terminal domain	Saccharopolyspora erythraea [TaxId: 1836]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
2fr0A00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain