PDB ID : 2h5l [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

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Secondary Structure


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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CC
DD
Title
S-ADENOSYLHOMOCYSTEINE HYDROLASE CONTAINING NAD AND 3-DEAZA-D- ERITADENINE

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
2h5l
17214973 X-RAY DIFFRACTION/2.8 3DD:(2R,3R)-4-(4-AMINO-1H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-2,3-DIHYDROXYBUTANOIC ACID
NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
136151 A:190-352Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsFormate/glycerate dehydrogenases, NAD-domainS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136152 A:2-189
A:353-431		Alpha and beta proteins (a/b)Flavodoxin-likeFormate/glycerate dehydrogenase catalytic domain-likeS-adenosylhomocystein hydrolaseS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136153 B:190-352Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsFormate/glycerate dehydrogenases, NAD-domainS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136154 B:2-189
B:353-431		Alpha and beta proteins (a/b)Flavodoxin-likeFormate/glycerate dehydrogenase catalytic domain-likeS-adenosylhomocystein hydrolaseS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136155 C:190-352Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsFormate/glycerate dehydrogenases, NAD-domainS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136156 C:2-189
C:353-431		Alpha and beta proteins (a/b)Flavodoxin-likeFormate/glycerate dehydrogenase catalytic domain-likeS-adenosylhomocystein hydrolaseS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136157 D:190-352Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsFormate/glycerate dehydrogenases, NAD-domainS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136158 D:2-189
D:353-431		Alpha and beta proteins (a/b)Flavodoxin-likeFormate/glycerate dehydrogenase catalytic domain-likeS-adenosylhomocystein hydrolaseS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136159 E:190-352Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsFormate/glycerate dehydrogenases, NAD-domainS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136160 E:2-189
E:353-431		Alpha and beta proteins (a/b)Flavodoxin-likeFormate/glycerate dehydrogenase catalytic domain-likeS-adenosylhomocystein hydrolaseS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136161 F:190-352Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsFormate/glycerate dehydrogenases, NAD-domainS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136162 F:2-189
F:353-431		Alpha and beta proteins (a/b)Flavodoxin-likeFormate/glycerate dehydrogenase catalytic domain-likeS-adenosylhomocystein hydrolaseS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136163 G:190-352Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsFormate/glycerate dehydrogenases, NAD-domainS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136164 G:2-189
G:353-431		Alpha and beta proteins (a/b)Flavodoxin-likeFormate/glycerate dehydrogenase catalytic domain-likeS-adenosylhomocystein hydrolaseS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136165 H:190-352Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsFormate/glycerate dehydrogenases, NAD-domainS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]
136166 H:2-189
H:353-431		Alpha and beta proteins (a/b)Flavodoxin-likeFormate/glycerate dehydrogenase catalytic domain-likeS-adenosylhomocystein hydrolaseS-adenosylhomocystein hydrolaseNorway rat (Rattus norvegicus) [TaxId: 10116]

CATH
CATH ID Node Class Architecture Topology Homology
2h5lA013.40.50.1480:3-Layer(aba) Sandwich:Rossmann fold:Adenosylhomocysteinase-like
2h5lA023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2h5lB013.40.50.1480:3-Layer(aba) Sandwich:Rossmann fold:Adenosylhomocysteinase-like
2h5lB023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2h5lC013.40.50.1480:3-Layer(aba) Sandwich:Rossmann fold:Adenosylhomocysteinase-like
2h5lC023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2h5lD013.40.50.1480:3-Layer(aba) Sandwich:Rossmann fold:Adenosylhomocysteinase-like
2h5lD023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2h5lE013.40.50.1480:3-Layer(aba) Sandwich:Rossmann fold:Adenosylhomocysteinase-like
2h5lE023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2h5lF013.40.50.1480:3-Layer(aba) Sandwich:Rossmann fold:Adenosylhomocysteinase-like
2h5lF023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2h5lG013.40.50.1480:3-Layer(aba) Sandwich:Rossmann fold:Adenosylhomocysteinase-like
2h5lG023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
2h5lH013.40.50.1480:3-Layer(aba) Sandwich:Rossmann fold:Adenosylhomocysteinase-like
2h5lH023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain