OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 2i9p [A4]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Style

Secondary Structure

Download

Slab plane

Direction	Proportion
From front	%
From back	%
Move slab

Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D

Title

CRYSTAL STRUCTURE OF HUMAN HYDROXYISOBUTYRATE DEHYDROGENASE COMPLEXED WITH NAD+

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
2i9p			Not in PubMed	X-RAY DIFFRACTION/2.55	NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A4]	[A4]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
204755	A:202-332	All alpha proteins	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	automated matches	automated matches	Human (Homo sapiens) [TaxId: 9606]
287787	A:40-40	Artifacts	Tags	Tags	Tags	N-terminal Tags	Synthetic
204754	A:41-201	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Human (Homo sapiens) [TaxId: 9606]
230784	B:202-335	All alpha proteins	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	automated matches	automated matches	Human (Homo sapiens) [TaxId: 9606]
287788	B:40-40	Artifacts	Tags	Tags	Tags	N-terminal Tags	Synthetic
230783	B:41-201	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Human (Homo sapiens) [TaxId: 9606]
204757	C:202-332	All alpha proteins	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	automated matches	automated matches	Human (Homo sapiens) [TaxId: 9606]
287789	C:40-40	Artifacts	Tags	Tags	Tags	N-terminal Tags	Synthetic
204756	C:41-201	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Human (Homo sapiens) [TaxId: 9606]
204759	D:202-332	All alpha proteins	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	automated matches	automated matches	Human (Homo sapiens) [TaxId: 9606]
287790	D:40-40	Artifacts	Tags	Tags	Tags	N-terminal Tags	Synthetic
204758	D:41-201	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Human (Homo sapiens) [TaxId: 9606]

CATH

CATH ID	Node	Architecture	Topology	Homology
2i9pA01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2i9pA02	1.10.1040.10	:Orthogonal Bundle	:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2	:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
2i9pB01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2i9pB02	1.10.1040.10	:Orthogonal Bundle	:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2	:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
2i9pC01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2i9pC02	1.10.1040.10	:Orthogonal Bundle	:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2	:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
2i9pD01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2i9pD02	1.10.1040.10	:Orthogonal Bundle	:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2	:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2