OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 2ntj [A4]

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Title

MYCOBACTERIUM TUBERCULOSIS INHA BOUND WITH PTH-NAD ADDUCT

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
2ntj			17227913	X-RAY DIFFRACTION/2.5	P1H:{(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-PROPYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}M ETHYL [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGENDIPHOSPHATE

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A4]	[A4]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
408153	A:2-2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Synthetic
138581	A:3-269	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Tyrosine-dependent oxidoreductases	Enoyl-ACP reductase	Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
408154	B:2-2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Synthetic
138582	B:3-269	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Tyrosine-dependent oxidoreductases	Enoyl-ACP reductase	Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
2ntjA00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2ntjB00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain