Color
ARa IRb
|
|
a AR:All Residues
b IR:Interface Residues
b IR:Interface Residues
Slab plane
Title
CATALYSIS ASSOCIATED CONFORMATIONAL CHANGES REVEALED BY HUMAN CD38 COMPLEXED WITH A NON-HYDROLYZABLE SUBSTRATE ANALOG
Structure Summary
| PDB ID | Mutant | OPM | Pub Med | Method/Resolution | HETNAM |
|---|---|---|---|---|---|
| 2pgj | 17591784 | X-RAY DIFFRACTION/1.71 | N1C:N1-CYCLIC INOSINE 5___sq___-DIPHOSPHORIBOSE |
| Chain Formula | ||
|---|---|---|
| Amino Acid sequence | SCOPe Family Level | CATH Homology Level |
| [A] | [A] | [A] |
Structual Classification
SCOPe
| SCOPe ID | Chain | Class | Fold | Superfamily | Family | Protein Domain | Species |
|---|---|---|---|---|---|---|---|
| 167178 | A: | Alpha and beta proteins (a/b) | Flavodoxin-like | N-(deoxy)ribosyltransferase-like | ADP ribosyl cyclase-like | ADP ribosyl cyclase | Human (Homo sapiens) [TaxId: 9606] |
| 167179 | B: | Alpha and beta proteins (a/b) | Flavodoxin-like | N-(deoxy)ribosyltransferase-like | ADP ribosyl cyclase-like | ADP ribosyl cyclase | Human (Homo sapiens) [TaxId: 9606] |
CATH
| CATH ID | Node | Class | Architecture | Topology | Homology |
|---|---|---|---|---|---|
| 2pgjA01 | 1.20.82.10 | :Up-down Bundle | :ADP Ribosyl Cyclase; Chain A, domain 1 | :ADP Ribosyl Cyclase; Chain A, domain 1 | |
| 2pgjA02 | 3.40.50.720 | :3-Layer(aba) Sandwich | :Rossmann fold | :NAD(P)-binding Rossmann-like Domain | |
| 2pgjB01 | 1.20.82.10 | :Up-down Bundle | :ADP Ribosyl Cyclase; Chain A, domain 1 | :ADP Ribosyl Cyclase; Chain A, domain 1 | |
| 2pgjB02 | 3.40.50.720 | :3-Layer(aba) Sandwich | :Rossmann fold | :NAD(P)-binding Rossmann-like Domain |
