OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 2tmg [A6]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Style

Secondary Structure

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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D
E	E
F	F

Title

THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT S128R, T158E, N117R, S160E

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
2tmg			10366510	X-RAY DIFFRACTION/2.9

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A6]	[A6]	[A6]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
30238	A:179-411	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Thermotoga maritima [TaxId: 2336]
33886	A:4-178	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Thermotoga maritima [TaxId: 2336]
30239	B:179-411	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Thermotoga maritima [TaxId: 2336]
33887	B:4-178	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Thermotoga maritima [TaxId: 2336]
30240	C:179-411	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Thermotoga maritima [TaxId: 2336]
33888	C:4-178	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Thermotoga maritima [TaxId: 2336]
30241	D:179-411	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Thermotoga maritima [TaxId: 2336]
33889	D:4-178	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Thermotoga maritima [TaxId: 2336]
30242	E:179-411	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Thermotoga maritima [TaxId: 2336]
33890	E:4-178	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Thermotoga maritima [TaxId: 2336]
30243	F:179-411	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	Glutamate dehydrogenase	Thermotoga maritima [TaxId: 2336]
33891	F:4-178	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	Glutamate dehydrogenase	Thermotoga maritima [TaxId: 2336]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
2tmgA01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
2tmgA02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2tmgB01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
2tmgB02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2tmgC01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
2tmgC02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2tmgD01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
2tmgD02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2tmgE01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
2tmgE02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2tmgF01	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
2tmgF02	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain