PDB ID : 2vq3 [A2]
Color
ARa IRb
|
|
a AR:All Residues
b IR:Interface Residues
b IR:Interface Residues
Slab plane
Title
CRYSTAL STRUCTURE OF THE MEMBRANE PROXIMAL OXIDOREDUCTASE DOMAIN OF HUMAN STEAP3, THE DOMINANT FERRIC REDUCTASE OF THE ERYTHROID TRANSFERRIN CYCLE
Structure Summary
| PDB ID | Mutant | OPM | Pub Med | Method/Resolution | HETNAM |
|---|---|---|---|---|---|
| 2vq3 | 18495927 | X-RAY DIFFRACTION/2 | CIT:CITRIC ACID NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE |
| Chain Formula | ||
|---|---|---|
| Amino Acid sequence | SCOPe Family Level | CATH Homology Level |
| [A2] | [A2] | [A2] |
Interfaces
| Interface ID | Chain | Inaterface Class |
Interface Type | Contact Type |
|---|---|---|---|---|
| 2vq3_AB | A B |
HN HN |
i1_CR(H21,N7)_HH(P1,S1)_HN(L1,S4) i1_CR(H21,N7)_HH(P1,S1)_HN(L1,S4) |
c1_RP(HH16,NN31,HN17,NH18,EN1)_HH(P1,A1,S2)_HN(L4,S4)_EN(S1) c1_RP(HH16,NN31,HN17,NH18,EN1)_HH(P1,A1,S2)_HN(L4,S4)_EN(S1) |
Interface Class
| Interface ID | Interface 1 | Interface 2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Domain | Number of contact residues | Binding site Class | Percentages of Secondary structures(%) | Domain | Number of contact residues | Binding site Class | Percentages of Secondary structures(%) | |||||
| H | E | N | H | E | N | |||||||
| 2vq3_AB | A | 16 | HN | 62.5 | 100 | 37.5 | B | 17 | HN | 64.7 | 0 | 35.3 |
Interface Type: Information for each interface
| Interface ID | chain | Number of contact residues | Number of elements | Number of contacts between Secondary structure elements | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HH | EE | HE | HN | EN | |||||||||||||||||||||
| Hn | En | Nn | H | E | N | R | L | P | A | S | P | A | S | Ph | Ah | Ih | P | A | S | L | S | L | S | ||
| 2vq3_AB | A | 10 | 16 | 6 | 3 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
| 2vq3_AB | B | 11 | 0 | 6 | 3 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Contact Type: Information of contacts between interfaces
| Interface ID | Number of residue pairs between SS elements | Number of contacts between Secondary structure elements | ||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| H-H | E-E | N-N | H-E | H-N | N-E | E-H | N-H | E-N | H-H | E-E | H-E | H-N | E-N | |||||||||||||||
| P | A | S | Ih | P | A | S | IPh | IAh | P | A | S | Ih | L | S | Ih | L | S | Ih | ||||||||||
| 2vq3_AB | 17 | 0 | 16 | 0 | 5 | 0 | 0 | 2 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 2 | 0 | 0 | 0 |
Structual Classification
SCOPe
| SCOPe ID | Chain | Class | Fold | Superfamily | Family | Protein Domain | Species |
|---|---|---|---|---|---|---|---|
| x33702 | _ | Not Classified | Not Classified 337 | Not Classified 337 | Not Classified 337 | Not Classified 337 | Not Classified 33702 |
CATH
| CATH ID | Node | Class | Architecture | Topology | Homology |
|---|---|---|---|---|---|
| 2vq3A00 | 3.40.50.720 | :3-Layer(aba) Sandwich | :Rossmann fold | :NAD(P)-binding Rossmann-like Domain | |
| 2vq3B00 | 3.40.50.720 | :3-Layer(aba) Sandwich | :Rossmann fold | :NAD(P)-binding Rossmann-like Domain |
