OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 2vyn [A3B]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Style

Secondary Structure

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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D

Title

STRUCTURE OF E.COLI GAPDH RAT SPERM GAPDH HETEROTETRAMER

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
2vyn			19542219	X-RAY DIFFRACTION/2.2	CSD:3-SULFINOALANINE CSX:S-OXY CYSTEINE FMT:FORMIC ACID NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A3B]	[A3B]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
153707	A:0-146 A:311-329	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	Escherichia coli [TaxId: 562]
153708	A:147-310	Alpha and beta proteins (a+b)	FwdE/GAPDH domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	GAPDH-like	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	Escherichia coli [TaxId: 562]
153709	B:0-146 B:311-329	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	Escherichia coli [TaxId: 562]
153710	B:147-310	Alpha and beta proteins (a+b)	FwdE/GAPDH domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	GAPDH-like	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	Escherichia coli [TaxId: 562]
153711	C:0-146 C:311-329	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	Escherichia coli [TaxId: 562]
153712	C:147-310	Alpha and beta proteins (a+b)	FwdE/GAPDH domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	GAPDH-like	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	Escherichia coli [TaxId: 562]

CATH

CATH ID	Node	Architecture	Topology	Homology
2vynA01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2vynA02	3.30.360.10	:2-Layer Sandwich	:Dihydrodipicolinate Reductase; domain 2	:Dihydrodipicolinate Reductase; domain 2
2vynB01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2vynB02	3.30.360.10	:2-Layer Sandwich	:Dihydrodipicolinate Reductase; domain 2	:Dihydrodipicolinate Reductase; domain 2
2vynC01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2vynC02	3.30.360.10	:2-Layer Sandwich	:Dihydrodipicolinate Reductase; domain 2	:Dihydrodipicolinate Reductase; domain 2
2vynD01	3.40.50.720	:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2vynD02	3.30.360.10	:2-Layer Sandwich	:Dihydrodipicolinate Reductase; domain 2	:Dihydrodipicolinate Reductase; domain 2