OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 2x22 [A4]

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Title

CRYSTAL STRUCTURE OF M. TUBERCULOSIS INHA INHIBITED BY PT70

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
2x22			20200152	X-RAY DIFFRACTION/2.1	DMS:DIMETHYL SULFOXIDE NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE TCU:5-HEXYL-2-(2-METHYLPHENOXY)PHENOL

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A4]	[A4]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
169811	A:	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Tyrosine-dependent oxidoreductases	Enoyl-ACP reductase	Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
169812	B:	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Tyrosine-dependent oxidoreductases	Enoyl-ACP reductase	Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
2x22A00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2x22B00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain