OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 2zqz [A4]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Style

Secondary Structure

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Slab plane

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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	A
D	B

Title

R-STATE STRUCTURE OF ALLOSTERIC L-LACTATE DEHYDROGENASE FROM LACTOBACILLUS CASEI

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
2zqz			19787773	X-RAY DIFFRACTION/2.5	SO4:SULFATE ION

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A4]	[A4]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
207950	A:163-329	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Lactobacillus casei [TaxId: 1582]
207949	A:17-162	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Lactobacillus casei [TaxId: 1582]
207952	B:163-330	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Lactobacillus casei [TaxId: 1582]
207951	B:17-162	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Lactobacillus casei [TaxId: 1582]
207954	C:163-328	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Lactobacillus casei [TaxId: 1582]
207953	C:17-162	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Lactobacillus casei [TaxId: 1582]
207956	D:163-329	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Lactobacillus casei [TaxId: 1582]
207955	D:17-162	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Lactobacillus casei [TaxId: 1582]
207958	E:163-329	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Lactobacillus casei [TaxId: 1582]
207957	E:17-162	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Lactobacillus casei [TaxId: 1582]
207960	F:163-330	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Lactobacillus casei [TaxId: 1582]
207959	F:17-162	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Lactobacillus casei [TaxId: 1582]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
2zqzA01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2zqzA02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
2zqzB01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2zqzB02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
2zqzC01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2zqzC02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
2zqzD01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2zqzD02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
2zqzE01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2zqzE02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
2zqzF01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
2zqzF02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal