OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 3e1k [A2][a2]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Style

Secondary Structure

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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D

Title

CRYSTAL STRUCTURE OF KLUYVEROMYCES LACTIS GAL80P IN COMPLEX WITH THE ACIDIC ACTIVATION DOMAIN OF GAL4P

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
3e1k			18701455	X-RAY DIFFRACTION/3

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A2][a2]	[A2][a2]	[A2][a2]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
157971	A:14-154 A:374-457	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
157972	A:155-373	Alpha and beta proteins (a+b)	FwdE/GAPDH domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	Glucose 6-phosphate dehydrogenase-like	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
291736	A:458-459	Artifacts	Tags	Tags	Tags	C-terminal Tags	Synthetic
157973	C:14-154 C:374-457	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
157974	C:155-373	Alpha and beta proteins (a+b)	FwdE/GAPDH domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	Glucose 6-phosphate dehydrogenase-like	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
157975	E:14-154 E:374-457	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
157976	E:155-373	Alpha and beta proteins (a+b)	FwdE/GAPDH domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	Glucose 6-phosphate dehydrogenase-like	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
157977	G:14-154 G:374-457	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
157978	G:155-373	Alpha and beta proteins (a+b)	FwdE/GAPDH domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	Glucose 6-phosphate dehydrogenase-like	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
157979	I:14-154 I:374-457	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
157980	I:155-373	Alpha and beta proteins (a+b)	FwdE/GAPDH domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	Glucose 6-phosphate dehydrogenase-like	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
157981	K:14-154 K:374-457	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
157982	K:155-373	Alpha and beta proteins (a+b)	FwdE/GAPDH domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	Glucose 6-phosphate dehydrogenase-like	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
157983	M:14-154 M:374-457	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
157984	M:155-373	Alpha and beta proteins (a+b)	FwdE/GAPDH domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	Glucose 6-phosphate dehydrogenase-like	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
157985	O:14-154 O:374-457	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
157986	O:155-373	Alpha and beta proteins (a+b)	FwdE/GAPDH domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	Glucose 6-phosphate dehydrogenase-like	Galactose/lactose metabolism regulatory protein GAL80	Milk yeast (Kluyveromyces lactis) [TaxId: 28985]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
3e1kA01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
3e1kA02	3.30.360.10		:2-Layer Sandwich	:Dihydrodipicolinate Reductase; domain 2	:Dihydrodipicolinate Reductase; domain 2
3e1kC01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
3e1kC02	3.30.360.10		:2-Layer Sandwich	:Dihydrodipicolinate Reductase; domain 2	:Dihydrodipicolinate Reductase; domain 2
3e1kE01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
3e1kE02	3.30.360.10		:2-Layer Sandwich	:Dihydrodipicolinate Reductase; domain 2	:Dihydrodipicolinate Reductase; domain 2
3e1kG01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
3e1kG02	3.30.360.10		:2-Layer Sandwich	:Dihydrodipicolinate Reductase; domain 2	:Dihydrodipicolinate Reductase; domain 2
3e1kI01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
3e1kI02	3.30.360.10		:2-Layer Sandwich	:Dihydrodipicolinate Reductase; domain 2	:Dihydrodipicolinate Reductase; domain 2
3e1kK01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
3e1kK02	3.30.360.10		:2-Layer Sandwich	:Dihydrodipicolinate Reductase; domain 2	:Dihydrodipicolinate Reductase; domain 2
3e1kM01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
3e1kM02	3.30.360.10		:2-Layer Sandwich	:Dihydrodipicolinate Reductase; domain 2	:Dihydrodipicolinate Reductase; domain 2
3e1kO01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
3e1kO02	3.30.360.10		:2-Layer Sandwich	:Dihydrodipicolinate Reductase; domain 2	:Dihydrodipicolinate Reductase; domain 2