PDB ID : 3kou [A]
Color
ARa IRb
|
|
a AR:All Residues
b IR:Interface Residues
b IR:Interface Residues
Slab plane
Title
STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM OF CD38: EVIDENCE FOR A CONFORMATIONALLY FLEXIBLE COVALENT ENZYME-SUBSTRATE COMPLEX.
Structure Summary
| PDB ID | Mutant | OPM | Pub Med | Method/Resolution | HETNAM |
|---|---|---|---|---|---|
| 3kou | 22529956 | X-RAY DIFFRACTION/1.78 | 2NF:[[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXYOXOLAN-2-YL]METHOXY-HYDROXYPHOSPHORYL] [(2R,3S,4R,5R)-5-(3-CARBAMOYLPYRIDIN-1-IUM-1YL)- 3-FLUORO-,4- HYDROXYOXOLAN-2-YL]METHYL PHOSPHATE NAG:2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE SO4:SULFATE ION |
| Chain Formula | ||
|---|---|---|
| Amino Acid sequence | SCOPe Family Level | CATH Homology Level |
| [A] | [A] | [A] |
Structual Classification
SCOPe
| SCOPe ID | Chain | Class | Fold | Superfamily | Family | Protein Domain | Species |
|---|---|---|---|---|---|---|---|
| 179506 | A: | Alpha and beta proteins (a/b) | Flavodoxin-like | N-(deoxy)ribosyltransferase-like | automated matches | automated matches | Cow (Bos taurus) [TaxId: 9913] |
| 179507 | B: | Alpha and beta proteins (a/b) | Flavodoxin-like | N-(deoxy)ribosyltransferase-like | automated matches | automated matches | Cow (Bos taurus) [TaxId: 9913] |
CATH
| CATH ID | Node | Class | Architecture | Topology | Homology |
|---|---|---|---|---|---|
| 3kouA01 | 1.20.82.10 | :Up-down Bundle | :ADP Ribosyl Cyclase; Chain A, domain 1 | :ADP Ribosyl Cyclase; Chain A, domain 1 | |
| 3kouA02 | 3.40.50.720 | :3-Layer(aba) Sandwich | :Rossmann fold | :NAD(P)-binding Rossmann-like Domain | |
| 3kouB01 | 1.20.82.10 | :Up-down Bundle | :ADP Ribosyl Cyclase; Chain A, domain 1 | :ADP Ribosyl Cyclase; Chain A, domain 1 | |
| 3kouB02 | 3.40.50.720 | :3-Layer(aba) Sandwich | :Rossmann fold | :NAD(P)-binding Rossmann-like Domain |
