OLIGAMI : Oligomer Architecture and Molecular Interface

Title

ATG8 TRANSFER FROM ATG7 TO ATG3: A DISTINCTIVE E1-E2 ARCHITECTURE AND MECHANISM IN THE AUTOPHAGY PATHWAY

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
3t7e			22055190	X-RAY DIFFRACTION/2.25	ZN:ZINC ION

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A2]	[A2]	[A2]

Interfaces

Interface ID	Chain	Inaterface Class	Interface Type	Contact Type
3t7e_AB	A B	HEN HEN	i12_CR(H17,E4,N10)_CE(H4,E2,N4,C1)_HH(S1)_HE(S2)_HN(L1,S5)_EN(S2) i12_CR(H17,E4,N10)_CE(H4,E2,N4,C1)_HH(S1)_HE(S2)_HN(L1,S5)_EN(S2)	c4_RP(HH8,EE3,NN19,HE3,HN10,NE8,EH3,NH10,EN7)_HH(A1,S2)_EE(S1)_HE(S3)_HN(L2,S6)_EN(L2,S4) c4_RP(HH8,EE3,NN19,HE3,HN10,NE8,EH3,NH10,EN7)_HH(A1,S2)_EE(S1)_HE(S3)_HN(L2,S6)_EN(L2,S4)

Interface Class

Interface ID	Interface 1						Interface 2
	Domain	Number of contact residues	Binding site Class	Percentages of Secondary structures(%)			Domain	Number of contact residues	Binding site Class	Percentages of Secondary structures(%)
	Domain	Number of contact residues	Binding site Class	H	E	N	Domain	Number of contact residues	Binding site Class	H	E	N
3t7e_AB	A	57	HEN	49.1	100	42.1	B	57	HEN	49.1	8.8	42.1

Interface Type: Information for each interface

Interface ID	chain	Number of contact residues			Number of elements					Number of contacts between Secondary structure elements
		Number of contact residues			Number of elements					HH			EE						HE			HN		EN
		Hn	En	Nn	H	E	N	R	L	P	A	S	P	A	S	Ph	Ah	Ih	P	A	S	L	S	L	S
3t7e_AB	A	28	57	24	5	3	10	2	0	0	0	5	0	0	2	0	0	0	0	0	2	3	11	0	4
3t7e_AB	B	28	5	24	5	3	10	2	0	0	0	5	0	0	2	0	0	0	0	0	2	3	11	0	4

Contact Type: Information of contacts between interfaces

Interface ID	Number of residue pairs between SS elements									Number of contacts between Secondary structure elements
	H-H	E-E	N-N	H-E	H-N	N-E	E-H	N-H	E-N	H-H				E-E					H-E				H-N			E-N
	H-H	E-E	N-N	H-E	H-N	N-E	E-H	N-H	E-N	P	A	S	Ih	P	A	S	IPh	IAh	P	A	S	Ih	L	S	Ih	L	S	Ih
3t7e_AB	49	1	20	1	29	8	1	29	8	0	6	7	0	0	0	1	0	0	0	0	2	0	8	12	2	2	4	2

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
x17807	_	Not Classified	Not Classified 178	Not Classified 178	Not Classified 178	Not Classified 178	Not Classified 17807

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
3t7eA00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain