PDB ID : 4ajj [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

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Secondary Structure


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Slab plane

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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CC
DD
Title
RAT LDHA IN COMPLEX WITH 2-((3,4-DIMETHOXYPHENYL)METHYL))PROPANEDIOIC ACID AND N-(2-METHYL-1,3-BENZOTHIAZOL-6-YL)-3-UREIDO-PROPANAMIDE

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
4ajj
22417091 X-RAY DIFFRACTION/1.75 88R:2-((3,4-DIMETHOXYPHENYL)METHYL))PROPANEDIOIC ACID
88S:N-(2-METHYL-1,3-BENZOTHIAZOL-6-YL)-3-UREIDO-PROPANAMIDE
DMS:DIMETHYL SULFOXIDE
GOL:GLYCEROL
MLI:MALONATE ION
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
218958 A:160-331Alpha and beta proteins (a+b)LDH C-terminal domain-likeLDH C-terminal domain-likeLactate & malate dehydrogenases, C-terminal domainautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]
218957 A:2-159Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]
218960 B:160-331Alpha and beta proteins (a+b)LDH C-terminal domain-likeLDH C-terminal domain-likeLactate & malate dehydrogenases, C-terminal domainautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]
218959 B:2-159Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]
218961 C:1-159Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]
218962 C:160-331Alpha and beta proteins (a+b)LDH C-terminal domain-likeLDH C-terminal domain-likeLactate & malate dehydrogenases, C-terminal domainautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]
218963 D:1-159Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]
218964 D:160-331Alpha and beta proteins (a+b)LDH C-terminal domain-likeLDH C-terminal domain-likeLactate & malate dehydrogenases, C-terminal domainautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]

CATH
CATH ID Node Class Architecture Topology Homology
4ajjA013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ajjA023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4ajjB013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ajjB023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4ajjC013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ajjC023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4ajjD013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ajjD023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal