PDB ID : 4al4 [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

Style





Secondary Structure


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Slab plane

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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CC
DD
Title
RAT LDHA IN COMPLEX WITH 2-((4-(2-((3-((2-METHYL-1,3-BENZOTHIAZOL-6- YL)AMINO)3-OXO-PROPYL)CARBAMOYLAMINO)ETHOXY) PHENYL) METHYLPROPANEDIOIC ACID

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
4al4
22417091 X-RAY DIFFRACTION/1.78 GOL:GLYCEROL
W7E:2-[[4-[2-[[3-[(2-METHYL-1,3-BENZOTHIAZOL-6-YL)AMINO]-3-OXIDANYLIDENE-PROPYL]CARBAMOYLAMINO]ETHOXY]PHENYL]METHYL]PROPANEDIOICACID
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
219021 A:160-331Alpha and beta proteins (a+b)LDH C-terminal domain-likeLDH C-terminal domain-likeLactate & malate dehydrogenases, C-terminal domainautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]
219020 A:2-159Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]
219023 B:160-331Alpha and beta proteins (a+b)LDH C-terminal domain-likeLDH C-terminal domain-likeLactate & malate dehydrogenases, C-terminal domainautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]
219022 B:2-159Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]
219024 C:1-159Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]
219025 C:160-331Alpha and beta proteins (a+b)LDH C-terminal domain-likeLDH C-terminal domain-likeLactate & malate dehydrogenases, C-terminal domainautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]
219026 D:1-159Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]
219027 D:160-331Alpha and beta proteins (a+b)LDH C-terminal domain-likeLDH C-terminal domain-likeLactate & malate dehydrogenases, C-terminal domainautomated matchesNorway rat (Rattus norvegicus) [TaxId: 10116]

CATH
CATH ID Node Class Architecture Topology Homology
4al4A013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4al4A023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4al4B013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4al4B023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4al4C013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4al4C023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4al4D013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4al4D023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal