Title
THE AEROPATH PROJECT AND PSEUDOMONAS AERUGINOSA HIGH-THROUGHPUT CRYSTALLOGRAPHIC STUDIES FOR ASSESSMENT OF POTENTIAL TARGETS IN EARLY STAGE DRUG DISCOVERY.
Structure Summary
PDB ID |
Mutant |
OPM |
Pub Med |
Method/Resolution |
HETNAM |
4avy |
|
|
23295481 |
X-RAY DIFFRACTION/2 |
|
Chain Formula |
Amino Acid sequence |
SCOPe Family Level |
CATH Homology Level |
[A2] |
[A2] |
[A2] |
Interfaces
Interface ID |
Chain |
Inaterface Class |
Interface Type |
Contact Type |
4avy_AB |
A B |
HEN
HEN |
i9_CR(H8,E4,N12)_CE(H2,E2,N4)_HE(S1)_HN(L1,S3)_EN(S2)
i8_CR(H11,E6,N14)_CE(H2,E2,N4)_HH(S1)_EE(Ah1)_HE(P1,S1)_HN(L1,S3)_EN(S4)
|
c8_RP(HH4,EE1,NN44,HN12,NE5,NH11,EN5)_HH(S1)_HN(L3,S4)_EN(L1,S3)
c1_RP(HH8,EE5,NN24,HE5,HN9,NE8,EH6,NH9,EN8)_HH(S1)_EE(A1,S2)_HE(P1,A1,S2)_HN(L2,S4)_EN(L2,S4)
|
Interface Class
Interface ID |
Interface 1 |
Interface 2 |
Domain |
Number of contact residues |
Binding site Class |
Percentages of Secondary structures(%) |
Domain |
Number of contact residues |
Binding site Class |
Percentages of Secondary structures(%) |
H |
E |
N |
H |
E |
N |
4avy_AB |
A |
36 |
HEN |
19.4 |
100 |
69.4 |
B |
37 |
HEN |
21.6 |
10.8 |
67.6 |
Interface Type: Information for each interface
Interface ID |
chain |
Number of contact residues |
Number of elements |
Number of contacts between Secondary structure elements |
HH |
EE |
HE |
HN |
EN |
Hn |
En |
Nn |
H |
E |
N |
R |
L |
P |
A |
S |
P |
A |
S |
Ph |
Ah |
Ih |
P |
A |
S |
L |
S |
L |
S |
4avy_AB |
A |
7 |
36 |
25 |
2 |
1 |
6 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
1 |
0 |
5 |
0 |
3 |
4avy_AB |
B |
8 |
4 |
25 |
2 |
1 |
6 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
1 |
0 |
1 |
0 |
5 |
0 |
3 |
Contact Type: Information of contacts between interfaces
Interface ID |
Number of residue pairs between SS elements |
Number of contacts between Secondary structure elements |
H-H |
E-E |
N-N |
H-E |
H-N |
N-E |
E-H |
N-H |
E-N |
H-H |
E-E |
H-E |
H-N |
E-N |
P |
A |
S |
Ih |
P |
A |
S |
IPh |
IAh |
P |
A |
S |
Ih |
L |
S |
Ih |
L |
S |
Ih |
4avy_AB |
5 |
2 |
50 |
2 |
11 |
6 |
1 |
11 |
6 |
0 |
1 |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
0 |
0 |
2 |
0 |
2 |
6 |
0 |
2 |
0 |
0 |
Structual Classification
SCOPe
CATH