OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 4b7u [A4]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Style

Secondary Structure

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Slab plane

Direction	Proportion
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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D

Title

PLASMODIUM FALCIPARUM L-LACTATE DEHYDROGENASE COMPLEXED WITH BICINE

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
4b7u			Not in PubMed	X-RAY DIFFRACTION/1.88	BCN:BICINE CA:CALCIUM ION EDO:1,2-ETHANEDIOL MPD:(4S)-2-METHYL-2,4-PENTANEDIOL

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A4]	[A4]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
219357	A:165-329	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
219356	A:18-164	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
296559	A:330-330	Artifacts	Tags	Tags	Tags	C-terminal Tags	Synthetic
219359	B:165-329	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
219358	B:18-164	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
296560	B:330-330	Artifacts	Tags	Tags	Tags	C-terminal Tags	Synthetic
219361	C:165-329	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
219360	C:18-164	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
296561	C:330-330	Artifacts	Tags	Tags	Tags	C-terminal Tags	Synthetic
219363	D:165-329	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	Lactate dehydrogenase	Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
219362	D:18-164	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	LDH N-terminal domain-like	Lactate dehydrogenase	Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
296562	D:330-331	Artifacts	Tags	Tags	Tags	C-terminal Tags	Synthetic

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
4b7uA01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
4b7uA02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4b7uB01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
4b7uB02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4b7uC01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
4b7uC02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4b7uD01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
4b7uD02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal