PDB ID : 4bqp [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

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Secondary Structure


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Slab plane

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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CA
DB
Title
MTB INHA COMPLEX WITH METHYL-THIAZOLE COMPOUND 7

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
4bqp
24107081 X-RAY DIFFRACTION/1.89 NA:SODIUM ION
NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE
VMY:(1S)-1-(5-{[1-(2,6-DIFLUOROBENZYL)-1H-PYRAZOL-3-YL]AMINO}-1,3,4-THIADIAZOL-2-YL)-1-(4-METHYL-1,3-THIAZOL-2-YL)ETHANOL
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
229515 A:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
229512 B:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
229509 C:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
229513 D:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
229514 E:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
229511 F:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]

CATH
CATH ID Node Class Architecture Topology Homology
4bqpA003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4bqpB003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4bqpC003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4bqpD003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4bqpE003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4bqpF003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain