PDB ID : 4ei2 [A]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

Style





Secondary Structure


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Slab plane

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Chain

Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
Title
CRYSTAL STRUCTURES OF MTHK RCK GATING RING BOUND TO BARIUM

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
4ei2
23085076 X-RAY DIFFRACTION/3.11 BA:BARIUM ION
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A] [A] [A]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
266191 A:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266192 A:245-336Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
297318 A:337-337ArtifactsTagsTagsTagsC-terminal TagsSynthetic
266193 B:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266194 B:245-336Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266195 C:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266196 C:245-336Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
297319 C:337-338ArtifactsTagsTagsTagsC-terminal TagsSynthetic
266197 D:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266198 D:245-336Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
297320 D:337-339ArtifactsTagsTagsTagsC-terminal TagsSynthetic
266199 E:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266200 E:245-336Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
297321 E:337-337ArtifactsTagsTagsTagsC-terminal TagsSynthetic
266201 F:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266202 F:245-336Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
297322 F:337-337ArtifactsTagsTagsTagsC-terminal TagsSynthetic
266203 G:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266204 G:245-336Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
297323 G:337-339ArtifactsTagsTagsTagsC-terminal TagsSynthetic
266205 H:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266206 H:245-336Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
297324 H:337-337ArtifactsTagsTagsTagsC-terminal TagsSynthetic
266207 I:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266208 I:245-336Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266209 J:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266210 J:245-336Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
297325 J:337-338ArtifactsTagsTagsTagsC-terminal TagsSynthetic
266211 K:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266212 K:245-336Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
297326 K:337-338ArtifactsTagsTagsTagsC-terminal TagsSynthetic
266213 L:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266214 L:245-336Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266215 M:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266216 M:245-336Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
297327 M:337-338ArtifactsTagsTagsTagsC-terminal TagsSynthetic
266217 N:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266218 N:245-336Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
297328 N:337-338ArtifactsTagsTagsTagsC-terminal TagsSynthetic
266219 O:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266220 O:245-335Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266221 P:115-244Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsPotassium channel NAD-binding domainautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]
266222 P:245-335Alpha and beta proteins (a+b)TrkA C-terminal domain-likeTrkA C-terminal domain-likeautomated matchesautomated matchesMethanothermobacter thermautotrophicus [TaxId: 187420]

CATH
CATH ID Node Class Architecture Topology Homology
4ei2A013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2A021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2A033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2B013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2B021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2B033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2C013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2C021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2C033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2D013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2D021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2D033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2E013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2E021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2E033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2F013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2F021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2F033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2G013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2G021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2G033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2H013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2H021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2H033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2I013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2I021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2I033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2J013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2J021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2J033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2K013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2K021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2K033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2L013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2L021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2L033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2M013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2M021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2M033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2N013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2N021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2N033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2O013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2O021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2O033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain
4ei2P013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4ei2P021.20.5.870:Up-down Bundle:Single alpha-helices involved in coiled-coils or other helix-helix interfaces:Voltage-gated potassium channel
4ei2P033.30.70.1450:2-Layer Sandwich:Alpha-Beta Plaits:Regulator of K+ conductance, C-terminal domain